Ogier J A, Klein J P, Niddam R, Frank R M
J Biol Buccale. 1985 Jun;13(2):105-12.
Antigens prepared from culture supernatants or whole cells of several cariogenic strains were examined by immunoelectrophoresis for their crossed antigenicity, with reference to Streptococcus mutans OMZ175, serotype f. Crossed immunoelectrophoresis revealed a crossreactivity between soluble extracellular and wall associated antigens of six strains of Streptococcus mutans and one strain of Streptococcus sanguis. Protease destroyed the immunoreactivity of crossreactive antigens. One of them was shown to be localized on the bacterial surface.
从几种致龋菌株的培养上清液或全细胞制备的抗原，参照变形链球菌OMZ175血清型f，通过免疫电泳检测其交叉抗原性。交叉免疫电泳显示，6株变形链球菌和1株血链球菌的可溶性细胞外抗原与细胞壁相关抗原之间存在交叉反应性。蛋白酶破坏了交叉反应抗原的免疫反应性。其中一种抗原被证明定位于细菌表面。
