Community Based Psychiatric Care Research Center, Nursing and Midwifery School, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Psychology, Shiraz University, Shiraz, Iran.
Sci Rep. 2024 Jul 9;14(1):15817. doi: 10.1038/s41598-024-65922-4.
This study aimed to determine the mediation role of hope in the relationship of resilience with depression, anxiety, and stress in caregivers of children and adolescents with cancer. This cross-sectional study was conducted on 200 caregivers of children and adolescents with cancer. Adult Hope Scale, Connor-Davidson Resilience Scale, and Depression, Anxiety and Stress (DAS) scales were used for data collection. The mediator and moderator model was tested using the SPSS macro PROCESS (Model 4, and 5). The mediator model (model 4) indicated that DAS significantly correlated with resilience (β = - 0.54, t-value = - 5.01, p < 0.001), and hope (β = - 0.84, t-value = - 3.45, p = 0.0007). Hope mediated the relationship between resilience and DAS among caregivers of children and adolescents with cancer (Effect = - 0.18, SE = 0.06, 95% CI - 0.33 to - 0.06). The mediator and moderator model (model 5) showed that female caregivers had a stronger correlation between resilience and DAS when compared to their male counterparts (β = - 0.56, t-value = - 3.90, p-value = 0.0001); also, hope mediated the relationship between resilience and DAS among caregivers of children and adolescents with cancer (Effect = - 0.20, SE = 0.08, 95% CI - 0.37 to - 0.04). In conclusion, hope was a mediator, and female caregivers were a moderator in the relationship of resilience with depression, anxiety, and stress, and its promotion might be effective among caregivers of children and adolescents with cancer. It seems that resilience, female caregivers, and hope may provide good protection against depression, anxiety, and stress in caregivers of cancer patients.
本研究旨在确定希望在儿童和青少年癌症照顾者的韧性与抑郁、焦虑和压力之间的关系中的中介作用。这项横断面研究共纳入 200 名儿童和青少年癌症照顾者。采用成人希望量表、康纳-戴维森韧性量表和抑郁、焦虑和压力量表（DAS）进行数据收集。使用 SPSS 宏 PROCESS（模型 4 和 5）测试中介和调节模型。中介模型（模型 4）表明，DAS 与韧性（β=-0.54，t 值=-5.01，p<0.001）和希望（β=-0.84，t 值=-3.45，p=0.0007）显著相关。希望在儿童和青少年癌症照顾者的韧性与 DAS 之间的关系中起中介作用（效应=-0.18，SE=0.06，95%CI=-0.33 至-0.06）。中介和调节模型（模型 5）表明，与男性相比，女性照顾者的韧性与 DAS 之间的相关性更强（β=-0.56，t 值=-3.90，p 值=0.0001）；此外，希望在儿童和青少年癌症照顾者的韧性与 DAS 之间的关系中起中介作用（效应=-0.20，SE=0.08，95%CI=-0.37 至-0.04）。总之，希望是韧性与抑郁、焦虑和压力关系的中介，女性照顾者是其关系的调节因素，在儿童和青少年癌症照顾者中促进希望可能是有效的。韧性、女性照顾者和希望似乎为癌症患者照顾者的抑郁、焦虑和压力提供了良好的保护。
