Ja'afar Nor Liyana, Mustapha Muzaimi, Mohamed Mahaneem, Hashim Sabarisah
Department of Physiology, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Department of Neurosciences, School of Medical Sciences, Universiti Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
Malays J Med Sci. 2024 Jun;31(3):75-91. doi: 10.21315/mjms2024.31.3.5. Epub 2024 Jun 27.
Post-stroke cognitive impairment (PSCI) is a common decline in cognitive abilities that occurs within 3 months after a stroke. During recovery, stroke survivors often experience varying degrees of cognitive decline, with some patients experiencing permanent cognitive deficits. Thus, it is crucial to prioritise recovery and rehabilitation after a stroke to promote optimal protection of and improvement in cognitive function. Honey derived from stingless bees has been linked to various therapeutic properties, including neuroprotective effects. However, scientific evidence for the mechanisms through which these honey supplements enhance cognitive function remains limited. This narrative review aims to provide an overview of the causes of PSCI, current treatments, the biomarkers influencing cognition in post-stroke patients and the potential of stingless bee honey (SBH) as a neuroprotective agent against the progression of PSCI.
中风后认知障碍（PSCI）是指中风后3个月内出现的认知能力普遍下降。在恢复过程中，中风幸存者经常会经历不同程度的认知衰退，一些患者会出现永久性认知缺陷。因此，中风后优先考虑恢复和康复以促进对认知功能的最佳保护和改善至关重要。无刺蜂蜂蜜具有多种治疗特性，包括神经保护作用。然而，这些蜂蜜补充剂增强认知功能的机制的科学证据仍然有限。本叙述性综述旨在概述PSCI的病因、当前治疗方法、影响中风后患者认知的生物标志物以及无刺蜂蜂蜜（SBH）作为预防PSCI进展的神经保护剂的潜力。
