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[冷等离子体在伤口愈合中的应用]

[Cold plasma in wound healing].

作者信息

Werra Ursula Elisabeth Maria, Dorweiler Bernhard

机构信息

Klinik und Poliklinik für Gefäßchirurgie, Vaskuläre und endovaskuläre Chirurgie, Uniklinik Köln, Kerpener Str. 62, 50937, Köln, Deutschland.

出版信息

Urologie. 2025 Jan;64(1):52-58. doi: 10.1007/s00120-024-02376-6. Epub 2024 Jul 10.

Abstract

Even today, not all wounds can be healed. Treatment, which often takes many years, is a burden for patients and is very cost-intensive. Therefore, additional procedures such as cold plasma are becoming increasingly popular. Active components of cold plasma include electromagnetic radiation and free radicals. The active principle is based on, among other things, damage to bacterial cells and positive interaction with epithelial and endothelial cells. Angiogenesis and cellular oxygen metabolism are stimulated. The evidence base is still limited and heterogeneous, as some results are contradictory and comparability is difficult. However, new, well-designed studies have confirmed previous findings. In order to create a solid database, further studies are needed.

摘要

即使在今天,并非所有伤口都能愈合。治疗往往需要数年时间,这对患者来说是一种负担,而且成本很高。因此,诸如冷等离子体等额外的治疗方法越来越受欢迎。冷等离子体的活性成分包括电磁辐射和自由基。其作用原理除其他外,基于对细菌细胞的损伤以及与上皮细胞和内皮细胞的积极相互作用。它能刺激血管生成和细胞氧代谢。证据基础仍然有限且参差不齐,因为一些结果相互矛盾,难以进行比较。然而,新的、设计良好的研究证实了先前的发现。为了建立一个坚实的数据库,还需要进一步的研究。

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