Taşkıran Kandeğer Burcu, Argun Mehmet, Tök Levent, Tök Özlem
Konya City Hospital, Department of Ophthalmology, Konya, Turkey.
Suleyman Demirel University, Medicine Faculty, Department of Ophthalmology, Isparta, Turkey.
GMS Ophthalmol Cases. 2024 Jun 25;14:Doc06. doi: 10.3205/oc000238. eCollection 2024.
Diabetic papillopathy (DP), a form of optic disc edema, is characterized by decreased visual acuity and mild to severe visual field defects. While there is no consensus about treatment, some publications report that intravitreal anti-vascular endothelial growth factor (anti-VEGF) injection may be beneficial. To our knowledge, however, no research reports on the effects of combining anti-VEGF injection and oral steroids in DP treatment. In this case report we present three DP cases that showed rapid improvement following therapy with intravitreal bevacizumab and oral steroids. Optic disc edemas were significantly decreased, and visual acuities were markedly increased in the first week of treatment. This report suggests that combined use of these therapies may be safely used in patients diagnosed with DP.
糖尿病性视乳头病变（DP）是视神经盘水肿的一种形式，其特征为视力下降以及轻至重度视野缺损。虽然对于治疗尚无共识，但一些出版物报道玻璃体内注射抗血管内皮生长因子（抗VEGF）可能有益。然而，据我们所知，尚无关于联合使用抗VEGF注射剂和口服类固醇治疗DP效果的研究报告。在本病例报告中，我们呈现了3例DP患者，他们在接受玻璃体内贝伐单抗和口服类固醇治疗后迅速好转。在治疗的第一周，视神经盘水肿明显减轻，视力显著提高。本报告表明，这些疗法的联合应用可安全用于诊断为DP的患者。
