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Obstructive sleep apnea, cognitive impairment, and dementia: is sleep microstructure an important feature?

作者信息

Marchi Nicola Andrea, Allali Gilles, Heinzer Raphael

机构信息

Center for Investigation and Research in Sleep, Department of Medicine, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

Leenaards Memory Center, Department of Clinical Neurosciences, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland.

出版信息

Sleep. 2024 Dec 11;47(12). doi: 10.1093/sleep/zsae161.

DOI:10.1093/sleep/zsae161
PMID:38995090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11632185/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8df/11632185/8a4caccd89df/zsae161_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8df/11632185/8a4caccd89df/zsae161_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b8df/11632185/8a4caccd89df/zsae161_fig1.jpg

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本文引用的文献

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2
Older adults at greater risk for Alzheimer's disease show stronger associations between sleep apnea severity in REM sleep and verbal memory.老年人群患阿尔茨海默病的风险较高，其 REM 睡眠中睡眠呼吸暂停严重程度与言语记忆之间的相关性更强。
Alzheimers Res Ther. 2024 May 9;16(1):102. doi: 10.1186/s13195-024-01446-3.
3
Obstructive sleep apnea during rapid eye movement sleep and cognitive performance in adults.
长期间歇性低氧暴露小鼠的认知功能、睡眠及神经炎症标志物
Int J Mol Sci. 2025 Feb 20;26(5):1815. doi: 10.3390/ijms26051815.
成人快速眼动睡眠期阻塞性睡眠呼吸暂停与认知表现
Sleep Med. 2024 Jan;113:34-40. doi: 10.1016/j.sleep.2023.11.017. Epub 2023 Nov 11.
4
Sleep Architecture, Obstructive Sleep Apnea, and Cognitive Function in Adults.成人的睡眠结构、阻塞性睡眠呼吸暂停和认知功能。
JAMA Netw Open. 2023 Jul 3;6(7):e2325152. doi: 10.1001/jamanetworkopen.2023.25152.
5
Donanemab in Early Symptomatic Alzheimer Disease: The TRAILBLAZER-ALZ 2 Randomized Clinical Trial.多奈哌齐治疗早期症状性阿尔茨海默病的随机临床试验。
JAMA. 2023 Aug 8;330(6):512-527. doi: 10.1001/jama.2023.13239.
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Obstructive sleep apnea and cognitive functioning in the older general population: The moderating effect of age, sex, ApoE4, and obesity.老年人群中阻塞性睡眠呼吸暂停与认知功能的关系：年龄、性别、ApoE4 和肥胖的调节作用。
J Sleep Res. 2024 Feb;33(1):e13938. doi: 10.1111/jsr.13938. Epub 2023 Jun 13.
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