Critical and Intensive Care Medicine, Hospital Universitario Mayor-Méderi, Bogotá, Colombia.
Grupo de Investigación Clínica, Escuela de Medicina y Ciencias de la Salud, Universidad del Rosario, Bogotá, Colombia.
J Patient Rep Outcomes. 2024 Jul 12;8(1):70. doi: 10.1186/s41687-024-00748-2.
Patients with COVID-19 often experience severe long-term sequelae. This study aimed to assess resilience and Quality of Life (QoL) of patients who underwent mechanical ventilation due to COVID-19, one year after discharge.
This cross-sectional study enrolled patients who received mechanical ventilation for severe COVID-19 and were assessed one-year post-discharge. Participants completed a structured questionnaire via telephone comprising the Connor-Davidson Resilience Scale (CD-RISC) and the Post-COVID-19 Functional Status scale (PCFS). To establish the association between QoL and resilience, Spearman correlations were calculated between the PCFS and the CD-RISC. Linear regression models were adjusted to evaluate which factors were associated with QoL, with the total score of PCFS as the dependent variable.
A total of 225 patients were included in the analysis. The CD-RISC had a median score of 83 (IQR 74-91). The PCFS results showed that 61.3% (n = 138) of the patients were able to resume their daily activities without limitations. Among them, 37.3% (n = 84) were classified as Grade 0 and 24% (n = 54) as Grade 1. Mild and moderate functional limitations were found in 33.7% of the patients, with 24.8% (n = 56) classified as Grade 2 and 8.8% (n = 20) as Grade 3. Severe functional limitations (Grade 4) were observed in 4.8% (n = 11) of the patients. High CD-RISC scores were associated with lower levels of PCFS score (p < 0.001).
In this cohort of critically ill patients who underwent mechanical ventilation due to COVID-19, 38% of patients experienced a significant decline in their QoL one year after hospital discharge. Finally, a high level of resilience was strongly associated with better QoL one year after discharge.
COVID-19 患者常出现严重的长期后遗症。本研究旨在评估因 COVID-19 接受机械通气治疗并在出院后一年的患者的韧性和生活质量（QoL）。
这项横断面研究纳入了因严重 COVID-19 接受机械通气治疗并在出院后一年进行评估的患者。参与者通过电话完成了一份包含 Connor-Davidson 韧性量表（CD-RISC）和 COVID-19 后功能状态量表（PCFS）的结构化问卷。为了确定 QoL 与韧性之间的关联，使用 Spearman 相关系数计算了 PCFS 与 CD-RISC 之间的相关性。使用 PCFS 的总分作为因变量，调整线性回归模型以评估与 QoL 相关的因素。
共纳入 225 例患者进行分析。CD-RISC 的中位数评分为 83（IQR 74-91）。PCFS 结果显示，61.3%（n=138）的患者能够在无限制的情况下恢复日常活动。其中，37.3%（n=84）为 0 级，24%（n=54）为 1 级。33.7%的患者存在轻度和中度功能障碍，24.8%（n=56）为 2 级，8.8%（n=20）为 3 级。4.8%（n=11）的患者存在严重功能障碍（4 级）。高 CD-RISC 评分与 PCFS 评分较低相关（p<0.001）。
在因 COVID-19 接受机械通气治疗的这一危重症患者队列中，38%的患者在出院后一年的 QoL 显著下降。最后，高韧性与出院一年后 QoL 的改善密切相关。
