Ozaki Yousaku, Broughton Phil, Abdollahi Hamed, Valafar Homayoun, Blenda Anna V
Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC 29605, USA.
Department of Computer Science and Engineering, Molinaroli College of Engineering and Computing, Columbia, SC 29208, USA.
Cancers (Basel). 2024 Jul 3;16(13):2448. doi: 10.3390/cancers16132448.
Cancer is one of the leading causes of death, making timely diagnosis and prognosis very important. Utilization of AI (artificial intelligence) enables providers to organize and process patient data in a way that can lead to better overall outcomes. This review paper aims to look at the varying uses of AI for diagnosis and prognosis and clinical utility. PubMed and EBSCO databases were utilized for finding publications from 1 January 2020 to 22 December 2023. Articles were collected using key search terms such as "artificial intelligence" and "machine learning." Included in the collection were studies of the application of AI in determining cancer diagnosis and prognosis using multi-omics data, radiomics, pathomics, and clinical and laboratory data. The resulting 89 studies were categorized into eight sections based on the type of data utilized and then further subdivided into two subsections focusing on cancer diagnosis and prognosis, respectively. Eight studies integrated more than one form of omics, namely genomics, transcriptomics, epigenomics, and proteomics. Incorporating AI into cancer diagnosis and prognosis alongside omics and clinical data represents a significant advancement. Given the considerable potential of AI in this domain, ongoing prospective studies are essential to enhance algorithm interpretability and to ensure safe clinical integration.
癌症是主要死因之一,因此及时诊断和预后评估非常重要。利用人工智能(AI)可使医疗服务提供者以一种能带来更好总体结果的方式来组织和处理患者数据。这篇综述文章旨在探讨人工智能在诊断、预后评估及临床应用方面的不同用途。利用PubMed和EBSCO数据库查找2020年1月1日至2023年12月22日期间的出版物。通过使用“人工智能”和“机器学习”等关键搜索词来收集文章。收集的文章包括利用多组学数据、放射组学、病理组学以及临床和实验室数据进行人工智能在癌症诊断和预后评估中应用的研究。根据所使用的数据类型,将最终得到的89项研究分为八个部分,然后进一步细分为分别聚焦于癌症诊断和预后评估的两个子部分。八项研究整合了不止一种组学形式,即基因组学、转录组学、表观基因组学和蛋白质组学。将人工智能与组学及临床数据一起纳入癌症诊断和预后评估代表了一项重大进展。鉴于人工智能在该领域的巨大潜力,进行中的前瞻性研究对于提高算法的可解释性以及确保安全的临床整合至关重要。