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Integrating Omics Data and AI for Cancer Diagnosis and Prognosis.

作者信息

Ozaki Yousaku, Broughton Phil, Abdollahi Hamed, Valafar Homayoun, Blenda Anna V

机构信息

Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, SC 29605, USA.

Department of Computer Science and Engineering, Molinaroli College of Engineering and Computing, Columbia, SC 29208, USA.

出版信息

Cancers (Basel). 2024 Jul 3;16(13):2448. doi: 10.3390/cancers16132448.


DOI:10.3390/cancers16132448
PMID:39001510
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11240413/
Abstract

Cancer is one of the leading causes of death, making timely diagnosis and prognosis very important. Utilization of AI (artificial intelligence) enables providers to organize and process patient data in a way that can lead to better overall outcomes. This review paper aims to look at the varying uses of AI for diagnosis and prognosis and clinical utility. PubMed and EBSCO databases were utilized for finding publications from 1 January 2020 to 22 December 2023. Articles were collected using key search terms such as "artificial intelligence" and "machine learning." Included in the collection were studies of the application of AI in determining cancer diagnosis and prognosis using multi-omics data, radiomics, pathomics, and clinical and laboratory data. The resulting 89 studies were categorized into eight sections based on the type of data utilized and then further subdivided into two subsections focusing on cancer diagnosis and prognosis, respectively. Eight studies integrated more than one form of omics, namely genomics, transcriptomics, epigenomics, and proteomics. Incorporating AI into cancer diagnosis and prognosis alongside omics and clinical data represents a significant advancement. Given the considerable potential of AI in this domain, ongoing prospective studies are essential to enhance algorithm interpretability and to ensure safe clinical integration.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/f5946c26c766/cancers-16-02448-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/307bcb5c1827/cancers-16-02448-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/a76f82302aff/cancers-16-02448-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/16b92acac4a0/cancers-16-02448-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/f5946c26c766/cancers-16-02448-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/307bcb5c1827/cancers-16-02448-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/a76f82302aff/cancers-16-02448-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/16b92acac4a0/cancers-16-02448-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/01a9/11240413/f5946c26c766/cancers-16-02448-g002.jpg

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Integrating Omics Data and AI for Cancer Diagnosis and Prognosis.

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引用本文的文献

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Integrating tumor location into artificial intelligence-based prognostic models in cancer.

World J Clin Oncol. 2025-8-24

[2]
Deep learning-driven multi-omics analysis: enhancing cancer diagnostics and therapeutics.

Brief Bioinform. 2025-7-2

[3]
The Future of Tumor Markers: Advancing Early Malignancy Detection Through Omics Technologies, Continuous Monitoring, and Personalized Reference Intervals.

Biomolecules. 2025-7-14

[4]
AI-Powered Insights into Drug Resistance in Gastric Cancer: A Path Toward Precision Therapy.

Iran J Pharm Res. 2025-5-25

[5]
Advances in the use of Radiomics and Pathomics for predicting the efficacy of neoadjuvant therapy in tumors.

Transl Oncol. 2025-8

[6]
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Biomolecules. 2025-4-27

[7]
Role of multi‑omics in advancing the understanding and treatment of prostate cancer (Review).

Mol Med Rep. 2025-5

[8]
Artificial intelligence in gastroenterology: Ethical and diagnostic challenges in clinical practice.

World J Gastroenterol. 2025-3-14

[9]
Intraplaque haemorrhage quantification and molecular characterisation using attention based multiple instance learning.

medRxiv. 2025-3-26

[10]
AI-driven biomarker discovery: enhancing precision in cancer diagnosis and prognosis.

Discov Oncol. 2025-3-13

本文引用的文献

[1]
AI in medical diagnosis: AI prediction & human judgment.

Artif Intell Med. 2024-3

[2]
Radiomic signatures reveal multiscale intratumor heterogeneity associated with tissue tolerance and survival in re-irradiated nasopharyngeal carcinoma: a multicenter study.

BMC Med. 2023-11-27

[3]
A novel fusion algorithm for benign-malignant lung nodule classification on CT images.

BMC Pulm Med. 2023-11-28

[4]
Accurate prediction of HCC risk after SVR in patients with hepatitis C cirrhosis based on longitudinal data.

BMC Cancer. 2023-11-25

[5]
Deep learning approaches for differentiating thyroid nodules with calcification: a two-center study.

BMC Cancer. 2023-11-23

[6]
Selection of M7G-related lncRNAs in kidney renal clear cell carcinoma and their putative diagnostic and prognostic role.

BMC Urol. 2023-11-15

[7]
Machine learning-based prediction model and visual interpretation for prostate cancer.

BMC Urol. 2023-10-14

[8]
PB-LNet: a model for predicting pathological subtypes of pulmonary nodules on CT images.

BMC Cancer. 2023-10-3

[9]
Development and testing of a random forest-based machine learning model for predicting events among breast cancer patients with a poor response to neoadjuvant chemotherapy.

Eur J Med Res. 2023-9-30

[10]
Machine learning prediction models for different stages of non-small cell lung cancer based on tongue and tumor marker: a pilot study.

BMC Med Inform Decis Mak. 2023-9-29

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