帕金森病患者的认知在~4 Hz 时会出现波动。
Cognition falters at ~4 Hz in Parkinson's disease.
机构信息
Department of Neurology, University of Iowa, Iowa City, IA 52242, USA.
Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, USA.
出版信息
Trends Cogn Sci. 2024 Sep;28(9):789-791. doi: 10.1016/j.tics.2024.06.002. Epub 2024 Jul 12.
Abstract
Cognitive impairments are common in Parkinson's disease (PD). We have linked this deficit to attenuated midfrontal 1-8-Hz activity that fails to engage cortical cognitive networks. We discuss the consequences of these impairments and how they might be leveraged for PD-specific neurophysiological markers and for novel brain stimulation paradigms.
摘要
认知障碍在帕金森病（PD）中很常见。我们将这种缺陷与减弱的前额中 1-8-Hz 活动联系起来，这种活动无法使皮质认知网络参与其中。我们讨论了这些缺陷的后果，以及它们如何被用于 PD 特定的神经生理标记和新的脑刺激范式。
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