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Lower oddball event-related EEG delta and theta responses in patients with dementia due to Parkinson's and Lewy body than Alzheimer's disease.帕金森病和路易体痴呆患者的偶发性事件相关 EEG 德尔塔和 theta 反应低于阿尔茨海默病患者。
Neurobiol Aging. 2024 May;137:78-93. doi: 10.1016/j.neurobiolaging.2024.02.004. Epub 2024 Feb 16.
2
Theta frequency deep brain stimulation in the subthalamic nucleus improves working memory in Parkinson's disease.丘脑底核θ频段深部脑刺激改善帕金森病患者的工作记忆。
Brain. 2024 Apr 4;147(4):1190-1196. doi: 10.1093/brain/awad433.
3
Evoked mid-frontal activity predicts cognitive dysfunction in Parkinson's disease.诱发的额中部活动可预测帕金森病的认知功能障碍。
J Neurol Neurosurg Psychiatry. 2023 Nov;94(11):945-953. doi: 10.1136/jnnp-2022-330154. Epub 2023 Jun 1.
4
The way forward for cognition in Parkinson's disease.帕金森病认知功能研究的未来方向。
Prog Brain Res. 2022;269(1):457-462. doi: 10.1016/bs.pbr.2022.01.020. Epub 2022 Feb 4.
5
Cognitive effects of theta frequency bilateral subthalamic nucleus stimulation in Parkinson's disease: A pilot study.帕金森病患者双侧丘脑底核电刺激的认知影响：一项初步研究。
Brain Stimul. 2021 Mar-Apr;14(2):230-240. doi: 10.1016/j.brs.2020.12.014. Epub 2021 Jan 6.
6
Deep brain stimulation of the internal capsule enhances human cognitive control and prefrontal cortex function.内囊的深部脑刺激增强了人类的认知控制和前额叶皮层功能。
Nat Commun. 2019 Apr 4;10(1):1536. doi: 10.1038/s41467-019-09557-4.
7
Brain oscillations reveal impaired novelty detection from early stages of Parkinson's disease.脑电波显示帕金森病早期的新奇性检测受损。
Neuroimage Clin. 2018 Mar 22;18:923-931. doi: 10.1016/j.nicl.2018.03.024. eCollection 2018.
8
Mid-frontal theta activity is diminished during cognitive control in Parkinson's disease.帕金森病患者在进行认知控制时，额中θ频段活动减少。
Neuropsychologia. 2018 Aug;117:113-122. doi: 10.1016/j.neuropsychologia.2018.05.020. Epub 2018 May 23.
9
A pilot study of subthalamic theta frequency deep brain stimulation for cognitive dysfunction in Parkinson's disease.丘脑底核θ频率深部脑刺激治疗帕金森病认知功能障碍的一项初步研究。
Brain Stimul. 2018 Mar-Apr;11(2):456-458. doi: 10.1016/j.brs.2017.11.014. Epub 2017 Nov 23.
10
A human prefrontal-subthalamic circuit for cognitive control.人类前额叶-丘脑底核认知控制回路。
Brain. 2018 Jan 1;141(1):205-216. doi: 10.1093/brain/awx300.

帕金森病患者的认知在~4 Hz 时会出现波动。

Cognition falters at ~4 Hz in Parkinson's disease.

机构信息

Department of Neurology, University of Iowa, Iowa City, IA 52242, USA.

Department of Neurosurgery, University of Iowa, Iowa City, IA 52242, USA.

出版信息

Trends Cogn Sci. 2024 Sep;28(9):789-791. doi: 10.1016/j.tics.2024.06.002. Epub 2024 Jul 12.

DOI:10.1016/j.tics.2024.06.002
PMID:39003229
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11458154/
Abstract

Cognitive impairments are common in Parkinson's disease (PD). We have linked this deficit to attenuated midfrontal 1-8-Hz activity that fails to engage cortical cognitive networks. We discuss the consequences of these impairments and how they might be leveraged for PD-specific neurophysiological markers and for novel brain stimulation paradigms.

摘要

认知障碍在帕金森病（PD）中很常见。我们将这种缺陷与减弱的前额中 1-8-Hz 活动联系起来，这种活动无法使皮质认知网络参与其中。我们讨论了这些缺陷的后果，以及它们如何被用于 PD 特定的神经生理标记和新的脑刺激范式。