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病例报告:局部应用表皮生长因子能否被视为早产儿皮肤损伤的一种新疗法?

Case Report: Could topical epidermal growth factor be considered a new therapy for skin injuries in premature infants?

作者信息

Cossovel F, Marrazzo F, Nider S, Traunero A, Dussi G, Travan L, Cirino M, Zanon D

机构信息

Department of Neonatology, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.

Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

出版信息

Front Pediatr. 2024 Jun 28;12:1424191. doi: 10.3389/fped.2024.1424191. eCollection 2024.

Abstract

In this case report, we present the experience of a premature neonate born at 28 weeks of gestation who, following prolonged respiratory support, developed a pressure injury on the columella despite the implementation of all appropriate preventive techniques. This injury did not improve with standard therapies; therefore, it was necessary to apply a topical galenic therapy containing epidermal growth factor, resulting in complete healing of the lesion.

摘要

在本病例报告中,我们介绍了一名孕28周出生的早产儿的情况,该患儿在接受长时间呼吸支持后,尽管采取了所有适当的预防措施,鼻小柱仍出现了压疮。采用标准治疗方法后,该损伤并未改善;因此,有必要应用一种含有表皮生长因子的外用盖仑制剂疗法,最终使损伤完全愈合。

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