Suppr超能文献

预后营养指数对老年髋部骨折患者术后重症监护需求及死亡率的预测价值

Predictive value of prognostic nutritional index on postoperative intensive care requirement and mortality in geriatric hip fracture patients.

作者信息

Arslan Kadir, Celik Semih, Arslan Hale Cetin, Sahin Ayca Sultan, Genc Yasin, Erturk Cemil

机构信息

Department of Anesthesiology and Reanimation, University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital, Istanbul, Turkiye.

Department of Anesthesiology and Reanimation, Siirt Training and Research Hospital, Siirt, Turkiye.

出版信息

North Clin Istanb. 2024 Jun 26;11(3):249-257. doi: 10.14744/nci.2024.60430. eCollection 2024.

Abstract

OBJECTIVE

The incidence of postoperative morbidity and mortality in hip fracture patients is high and is associated with nutritional deficiencies. This study investigated the predictive value of preoperative prognostic nutritional index (PNI) on postoperative intensive care unit (ICU) requirement and mortality in geriatric hip fracture patients.

METHODS

Geriatric (≥65 years old) hip fracture patients who underwent surgery between January 2021 and September 2023 were evaluated retrospectively. Patients were classified according to the unit followed in the postoperative period (service group and ICU group) and 28-day mortality (mortality group and survivor group). The predictive value of PNI for ICU requirement and mortality and the factors affecting ICU requirement and mortality were investigated.

RESULTS

The study included two hundred twenty-two patients, and 66.2% (n=147) were women. In the postoperative period, 47.7% (n=106) of the patients were followed in the ICU and 52.3% (n=116) in the inpatient service. The 28-day mortality of the patients was 6.8% (n=15). PNI was found to be significantly lower in patients followed in the ICU (group ICU) than in those followed in the service (group S) and in patients who died (group mortality) compared to those who lived (group survivor) (p<0.001 and p=0.029, respectively). In multivariate regression analysis, high American Society of Anesthesiologists (ASA) status and low PNI were determined to be independent risk factors for ICU requirement. Acute Physiology and Chronic Health Assessment II score was an independent predictor of mortality. In ROC curve analysis, the cut-off value of PNI in predicting mortality was 32.5, and the area under the curve was 0.660 (95% CI, 0.516-0.803).

CONCLUSION

In geriatric hip fracture patients, preoperative PNI value can be used, like ASA status, in determining postoperative ICU requirements. Nutritional deficiencies are associated with adverse postoperative outcomes in this patient group, and low PNI values (<32.5) help predict in-hospital mortality.

摘要

目的

髋部骨折患者术后发病率和死亡率较高,且与营养缺乏有关。本研究探讨术前预后营养指数(PNI)对老年髋部骨折患者术后重症监护病房(ICU)需求及死亡率的预测价值。

方法

回顾性评估2021年1月至2023年9月期间接受手术的老年(≥65岁)髋部骨折患者。根据术后随访科室(服务组和ICU组)及28天死亡率(死亡组和存活组)对患者进行分类。研究PNI对ICU需求及死亡率的预测价值以及影响ICU需求和死亡率的因素。

结果

该研究纳入222例患者,其中66.2%(n = 147)为女性。术后,47.7%(n = 106)的患者在ICU接受随访,52.3%(n = 116)在住院病房接受随访。患者的28天死亡率为6.8%(n = 15)。发现ICU随访患者(ICU组)的PNI显著低于住院病房随访患者(S组),且死亡患者(死亡组)的PNI低于存活患者(存活组)(分别为p < 0.001和p = 0.029)。多因素回归分析确定,美国麻醉医师协会(ASA)分级高和PNI低是ICU需求的独立危险因素。急性生理与慢性健康状况评估II评分是死亡率的独立预测因素。在ROC曲线分析中,PNI预测死亡率的截断值为32.5,曲线下面积为0.660(95%CI,0.516 - 0.803)。

结论

在老年髋部骨折患者中,术前PNI值可像ASA分级一样用于确定术后ICU需求。营养缺乏与该患者群体术后不良结局相关,低PNI值(<32.5)有助于预测院内死亡率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcad/11237825/787b5607ff24/NCI-11-249-g001.jpg

相似文献

引用本文的文献

本文引用的文献

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验