Uygun Hatice, Varan Celal, Erdem Nurettin, Yavuz Sibel, Turgut Mehmet
Department of Pediatric Infectious Disease, Adiyaman University Training and Research Hospital, Adiyaman, Turkiye.
Department of Pediatric Cardiology, Adiyaman University Faculty of Medicine, Adiyaman, Turkiye.
North Clin Istanb. 2024 Jun 12;11(3):234-240. doi: 10.14744/nci.2023.56198. eCollection 2024.
In this study, it was aimed to show whether infection, which causes various cardiovascular complications in children, can lead to an increase in aortic stiffness with a noninvasive method, echocardiography.
Children who were diagnosed with infection and who had tachycardia, chest pain and murmur that were not related to body temperature increase during the treatment were evaluated cardiologically and had echocardiographic examination, were included in the study. Aortic strain, aortic distensibility measurement results and aortic stiffness index of the patients in the patient and control groups were calculated.
Our study included 53 cases with a mean age of 11.43±4.13 years in the patient group and 68 cases with a mean age of 10.16±3.61 years in the control group. We found that systolic blood pressure was lower in the patient group than in the control group (p=0.014). In the analysis of laboratory parameters, blood glucose level was found to be significantly higher in the patient group (p=0.001). In the statistical evaluation of aortic strain, aortic stiffness index and aortic distensibility measurement results between the patient and control groups, no statistically significant difference was found between the groups (p=0.287, p=0.784, p=0.208).
In our study, where we tried to show a new parameter that could contribute to the increase in aortic stiffness, the results showed that infection was not a factor that increased aortic stiffness in the pediatric age group.
本研究旨在通过超声心动图这种非侵入性方法，表明导致儿童各种心血管并发症的感染是否会导致主动脉僵硬度增加。
将诊断为感染且在治疗期间出现与体温升高无关的心动过速、胸痛和杂音的儿童纳入研究，进行心脏评估并接受超声心动图检查。计算患者组和对照组患者的主动脉应变、主动脉扩张性测量结果和主动脉僵硬度指数。
我们的研究包括患者组53例，平均年龄11.43±4.13岁，对照组68例，平均年龄10.16±3.61岁。我们发现患者组的收缩压低于对照组（p = 0.014）。在实验室参数分析中，发现患者组的血糖水平显著更高（p = 0.001）。在对患者组和对照组之间的主动脉应变、主动脉僵硬度指数和主动脉扩张性测量结果进行统计评估时，两组之间未发现统计学上的显著差异（p = 0.287，p = 0.784，p = 0.208）。
在我们试图展示一个可能导致主动脉僵硬度增加的新参数的研究中，结果表明感染不是儿童年龄组中增加主动脉僵硬度的因素。
