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前纵隔肿物病例中罕见的乳糜性心包积液

A Rare Occurrence of Chylopericardium in a Case of Anterior Mediastinal Mass.

作者信息

Maheswaran Nair Nadhu Krishna, Kurian Richu Bob, Thangakunam Balamugesh

机构信息

Pulmonary Medicine, Christian Medical College Vellore, Vellore, IND.

出版信息

Cureus. 2024 Jun 12;16(6):e62214. doi: 10.7759/cureus.62214. eCollection 2024 Jun.

Abstract

A middle-aged gentleman presented with dyspnea and hypotension, accompanied by an anterior mediastinal mass infiltrating the anterior chest wall and a moderate to large pericardial effusion, which upon evaluation revealed chylous fluid. Further investigation diagnosed him with right lung adenocarcinoma infiltrating the chest wall, staged at T4N3M1. The patient subsequently developed cardiac tamponade, necessitating immediate medical intervention. Management of the patient's cardiac tamponade involved pericardiocentesis via an indwelling pericardial catheter, allowing continuous drainage of the chylous fluid. Additionally, the patient was placed on a medium-chain triglyceride diet (MCTD) to reduce chyle production. These interventions resulted in significant symptomatic improvement, stabilizing the patient's hemodynamic status, and alleviating the immediate life-threatening condition. This case highlights the clinical challenges posed by rare presentations such as chylopericardium secondary to malignancy and emphasizes the importance of comprehensive diagnostic evaluation and prompt therapeutic management. The successful outcome, achieved through a combination of pericardial drainage and dietary modifications, underscores the critical role of a conservative approach in managing complex oncological cases with acute complications.

摘要

一名中年男性出现呼吸困难和低血压,伴有前纵隔肿块侵犯前胸壁及中到大量心包积液,经评估积液为乳糜液。进一步检查诊断为右肺腺癌侵犯胸壁,分期为T4N3M1。患者随后出现心脏压塞,需要立即进行医疗干预。对该患者心脏压塞的处理包括通过留置心包导管进行心包穿刺引流,以持续引流乳糜液。此外,患者接受中链甘油三酯饮食(MCTD)以减少乳糜生成。这些干预措施使症状得到显著改善,稳定了患者的血流动力学状态,缓解了危及生命的紧急情况。该病例凸显了诸如恶性肿瘤继发乳糜心包等罕见表现所带来的临床挑战,并强调了全面诊断评估和及时治疗管理的重要性。通过心包引流和饮食调整相结合取得的成功结果,突显了保守方法在处理伴有急性并发症的复杂肿瘤病例中的关键作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f23/11240195/1d932dbe6043/cureus-0016-00000062214-i01.jpg

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