Verma Rajesh, Lalla Rakesh, Babu Suresh
Department of Neurology, King George Medical University, Lucknow, Uttar Pradesh, India.
BMJ Case Rep. 2013 May 2;2013:bcr2013009666. doi: 10.1136/bcr-2013-009666.
Hepatitis B virus infection leads to multisystem manifestations owing to involvement of kidney, skin, vasculature, haematopoietic and nervous system. The hepatitis B infection can cause neuropathy either to vasculitis associated with polyarteritis nodosa or immune-mediated neural damage. In this submission, we report a young woman, who presented with mononeuritis multiplex and painful ulcerations as the first manifestation of chronic hepatitis B virus infection. The antiviral therapy along with steroids led to remarkable recovery. The clinical settings of hepatitis B virus infection should not be ignored in the presentation of mononeuritis multiplex with ulcers, although the commonest cause is leprosy in the Indian sub-continent.
乙型肝炎病毒感染可导致多系统表现，因为肾脏、皮肤、血管系统、造血系统和神经系统都会受累。乙型肝炎感染可因结节性多动脉炎相关的血管炎或免疫介导的神经损伤而导致神经病变。在本病例报告中，我们报道了一名年轻女性，她以多发性单神经炎和疼痛性溃疡为慢性乙型肝炎病毒感染的首发表现。抗病毒治疗联合使用类固醇导致了显著的康复。在出现伴有溃疡的多发性单神经炎时，不应忽视乙型肝炎病毒感染的临床情况，尽管在印度次大陆最常见的病因是麻风病。
