Lepenos Theocharis, Sanoudou Despina, Protogerou Athanase, Laios Konstantinos, Androutsos Georgios, Karamamou Marianna
History of Medicine and Medical Ethics, National and Kapodistrian University of Athens School of Medicine, Amfikleia, GRC.
Clinical Genomics and Pharmacogenomics Unit, 4th Department of Internal Medicine, Athens, GRC.
Cureus. 2024 Jun 17;16(6):e62543. doi: 10.7759/cureus.62543. eCollection 2024 Jun.
Infection control remains a significant burden for healthcare systems. The irrational use of antibiotics in the fight against microbial diseases has led to the fast development of antimicrobial resistance. Considering how the latter can adversely influence the effectiveness of modern treatments and the way medicine is practiced, we should revise the events that led to the establishment of the general principles of antisepsis and pay special tribute to the people who contributed to their formation, bearing in mind that they remain unmodified to a great extent until today. Without Semmelweis' conceptualization of the idea of direct transmission of sepsis, Pasteur's emblematic figure that helped promote the idea even further, and Lister's methodology structuring, the scientific community would have significantly delayed winning the battle against germs.
感染控制仍然是医疗系统的一项重大负担。在对抗微生物疾病过程中抗生素的不合理使用导致了抗菌药物耐药性的迅速发展。考虑到抗菌药物耐药性会对现代治疗的有效性以及医学实践方式产生不利影响，我们应该回顾促成防腐基本原则确立的事件，并特别向那些为这些原则的形成做出贡献的人致敬，要记住这些原则在很大程度上至今仍未改变。如果没有塞麦尔维斯对败血症直接传播概念的构想、巴斯德进一步推动这一理念的标志性人物形象以及李斯特的方法构建，科学界在战胜病菌的战斗中将会大幅延迟取得胜利。
