Bernoco M, Bernoco D, Danilovs J, Terasaki P I, Mollicone R, Oriol R
Tissue Antigens. 1985 Aug;26(2):147-52. doi: 10.1111/j.1399-0039.1985.tb00948.x.
Lymphocytotoxic antibodies to the red cell blood groups A and B were purified from human sera by elution from synthetic immunoadsorbents (Synsorbs from Chembiomed). The lymphocytotoxic activity of the eluted antibodies was better preserved when elution was carried out at pH 11, whereas it was less stable when elution was performed at pH3. In addition, complete removal of anti-red cell blood group activity from an anti-HLA serum was easily obtained by adsorption on the corresponding Synsorb without loss of anti-HLA activity.
通过从合成免疫吸附剂（Chembiomed公司的Synsorbs）上洗脱，从人血清中纯化出针对红细胞血型A和B的淋巴细胞毒性抗体。当在pH 11进行洗脱时，洗脱抗体的淋巴细胞毒性活性得到更好的保留，而在pH 3进行洗脱时其稳定性较差。此外，通过吸附在相应的Synsorb上可轻松实现从抗HLA血清中完全去除抗红细胞血型活性，且不会损失抗HLA活性。
