新生儿出血后心室扩张时的脑脊液压力
Cerebrospinal fluid pressure during post haemorrhagic ventricular dilatation in newborn infants.
作者信息
Kaiser A M, Whitelaw A G
出版信息
Arch Dis Child. 1985 Oct;60(10):920-4. doi: 10.1136/adc.60.10.920.
Abstract
Post haemorrhagic ventricular dilatation occurs in a minority of newborn infants, but is associated with a high risk of cerebral palsy and developmental delay. Neither the relation of ventricular size to cerebrospinal fluid (CSF) pressure, nor the effect of CSF removal on prognosis, have been established. Normal CSF pressure measured at subarachnoid cannulation was mean (SD) 2.8 (1.4) mm Hg. Values were significantly higher in post haemorrhagic ventricular dilatation--9.1 (3.7) mm Hg when the ventricles were expanding, and 4.5 (2.4) mm Hg when they were static or contracting. No significant relation between head circumference and CSF pressure was found in this series. Raised CSF pressure is associated with progressive ventricular dilatation, and may contribute to the increased risk of neurological abnormality.
摘要
出血后脑室扩张发生于少数新生儿，但与脑瘫和发育迟缓的高风险相关。脑室大小与脑脊液（CSF）压力之间的关系以及脑脊液引流对预后的影响均未明确。蛛网膜下腔置管测量的正常脑脊液压力平均（标准差）为2.8（1.4）mmHg。出血后脑室扩张时的值显著更高——脑室扩张时为9.1（3.7）mmHg，脑室静止或缩小 时为4.5（2.4）mmHg。本系列研究未发现头围与脑脊液压力之间存在显著关系。脑脊液压力升高与脑室进行性扩张相关，可能会增加神经异常的风险。
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