Centre for Primary Care and Health Services Research, Division of Population Health, The University of Manchester, Manchester, UK
Centre for Primary Care and Health Services Research, Division of Population Health, The University of Manchester, Manchester, UK.
BMJ Open. 2024 Jul 24;14(7):e076792. doi: 10.1136/bmjopen-2023-076792.
In the context of iterative feedback loops to support real-time policy decision making, and an emphasis on speeding up adoption of evidence-based interventions, qualitative healthcare researchers are increasingly expected to produce rapid results and products. Traditional qualitative methods have been adapted for this purpose.
To develop and apply a rapid analysis framework in a process evaluation for the VICTORION-Spirit study; a ground-breaking hybrid trial examining real-world delivery of inclisiran-a cholesterol-lowering treatment-in primary care.
We developed a rapid analysis framework, using a summary template, to analyse data from semistructured telephone interviews.
Primary care in Greater Manchester, UK.
Patients who had received inclisiran as part of the VICTORION-Spirit trial (56), providers delivering inclisiran (28) and representatives from the Academic Health Science Network (8) participated in the original study.
The rapid analysis framework we developed and applied comprised six steps: (1) creating a summary template based on the five Consolidated Framework for Implementation Research domains; (2) test-driving, refining and finalising the summary template; (3) completing the template soon after each interview using field notes; (4) discussing analysis as a team; (5) transferring summaries to a matrix; and (6) using the summary matrix to inform presentations and interim reports for stakeholders. Our rapid analysis framework saved time and improved efficiency, as we were able to feedback barriers to stakeholders in real time via presentations.
Rapid analysis in applied healthcare research can produce timely and trustworthy findings. Our rapid analysis framework would be useful within studies where there is a need to feedback to stakeholders and adjust implementation strategies accordingly in real time. Thus, supporting successful implementation efforts and accelerating adoption.
NCT04807400, 19/03/2021.
在支持实时政策决策的迭代反馈循环中，并且强调加快采用基于证据的干预措施，医学研究人员越来越需要提供快速的结果和产品。为此，传统的定性方法已经过调整以适应此目的。
在 VICTORION-Spirit 研究的过程评估中开发和应用快速分析框架；这是一项开创性的混合试验，研究了在初级保健中实际提供inclisiran（一种降低胆固醇的治疗方法）。
我们开发了一个快速分析框架，使用摘要模板来分析半结构化电话访谈的数据。
英国大曼彻斯特的初级保健。
参加 VICTORION-Spirit 试验的患者（56 名）、提供 inclisiran 的提供者（28 名）和学术健康科学网络的代表（8 名）参加了原始研究。
我们开发并应用的快速分析框架包括六个步骤：（1）根据五个实施研究综合框架领域创建摘要模板；（2）试用、改进和最终确定摘要模板；（3）使用现场笔记在每次访谈后尽快完成模板；（4）团队讨论分析；（5）将摘要转移到矩阵中；（6）使用摘要矩阵为利益相关者提供信息。我们的快速分析框架节省了时间并提高了效率，因为我们能够通过演示实时向利益相关者反馈障碍。
在应用医疗保健研究中，快速分析可以产生及时且值得信赖的结果。我们的快速分析框架在需要及时向利益相关者反馈并相应地实时调整实施策略的研究中非常有用。从而支持成功的实施工作并加速采用。
NCT04807400，2021 年 3 月 19 日。
