Sameshima Seiji, Yamashita Takehiro, Terasaki Hiroto, Asaoka Ryo, Yoshihara Naoya, Kakiuchi Naoko, Sakamoto Taiji
Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshima, Japan.
Department of Ophthalmology, Seirei Hamamatsu General Hospital, Shizuoka, Japan.
Int J Retina Vitreous. 2024 Jul 25;10(1):51. doi: 10.1186/s40942-024-00570-4.
To investigate the relationship between changes in the optic disc size and color, cup-to-disc (C/D) ratio, and axial elongation in schoolchildren.
A prospective cohort study was performed in 75 right eyes of elementary school students for six years (from 8.5 to 14.5 years old). In the first and last year, all participants underwent optical axial length measurement and color fundus photography. The optic disc color was calculated by dividing the intensity of red by the sum of the intensity of red, green, and blue. The optic disc area was calculated by modifying the number of pixels according to Bennett's formula. The C/D ratio was calculated by dividing the vertical cup diameter by vertical optic disc diameter. Wilcoxon signed rank test was used to compare these optic disc parameters and axial length in the first and last year.
Mean axial length in the last year (24.82 mm) was significantly longer than that in the first year (23.34 mm). Likewise, the mean optic disc size was significantly smaller in the last year (41,946 pixels) than that in the first year (46,144 pixels). The mean optic disc color in the last year (0.49) was significantly more reddish than that in the first year (0.46), while the mean C/D ratio in last year (0.50) was significantly smaller than that in first year (0.52).
During the period from 8.5 years to 14.5 years of age, both the optic disc size and C/D ratio became smaller, while the color became more red.
探讨学龄儿童视盘大小和颜色变化、杯盘比（C/D）与眼轴长度之间的关系。
对75名小学生的右眼进行了为期六年（8.5至14.5岁）的前瞻性队列研究。在第一年和最后一年，所有参与者均接受了眼轴长度测量和彩色眼底照相。视盘颜色通过红色强度除以红色、绿色和蓝色强度之和来计算。视盘面积根据贝内特公式修改像素数量来计算。C/D比通过垂直杯径除以垂直视盘直径来计算。采用Wilcoxon符号秩检验比较第一年和最后一年的这些视盘参数和眼轴长度。
最后一年的平均眼轴长度（24.82毫米）显著长于第一年（23.34毫米）。同样，最后一年的平均视盘大小（41,946像素）显著小于第一年（46,144像素）。最后一年的平均视盘颜色（0.49）比第一年（0.46）明显更红，而最后一年的平均C/D比（0.50）显著小于第一年（0.52）。
在8.5岁至14.5岁期间，视盘大小和C/D比均变小，而颜色变得更红。
