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可调节风险的交集:孤独与处于阿尔茨海默病风险中的老年女性较差的主观睡眠质量相关。

Intersections of Modifiable Risks: Loneliness is Associated with Poor Subjective Sleep Quality in Older Women at Risk for Alzheimer's Disease.

机构信息

MADURA ADAR Program, University of California, San Diego, La Jolla, CA, USA.

Department of Neurosciences, University of California, San Diego, La Jolla, CA, USA.

出版信息

Int J Aging Hum Dev. 2024 Dec;99(4):505-520. doi: 10.1177/00914150241255888. Epub 2024 Jul 26.

DOI:10.1177/00914150241255888
PMID:39054949
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11490093/
Abstract

We examined the relationship between subjective and objective sleep outcomes and loneliness in older women at risk for Alzheimer's disease (AD). Our sample consisted of 39 participants (aged 65+) with mild cognitive deficits who completed the UCLA Loneliness Scale, the Pittsburgh Sleep Quality Index (PSQI), and an at home sleep test, to determine presence of obstructive sleep apnea. Based on sleep quality scores, individuals categorized as "poor sleepers" had significantly higher loneliness scores than "good sleepers." However, total loneliness scores did not significantly differ between groups with or without sleep apnea. We found that higher loneliness was significantly associated to lower habitual sleep efficiency and sleep duration and was also influenced by use of sleep medication. Our findings suggest that increased loneliness relates to worse subjective sleep quality, but not to sleep apnea. These findings suggest that combined interventions targeting loneliness and sleep quality may be important for older women.

摘要

我们研究了处于阿尔茨海默病(AD)风险中的老年女性的主观和客观睡眠结果与孤独感之间的关系。我们的样本由 39 名认知功能轻度受损的参与者(年龄在 65 岁以上)组成,他们完成了 UCLA 孤独感量表、匹兹堡睡眠质量指数(PSQI)和在家中的睡眠测试,以确定是否存在阻塞性睡眠呼吸暂停。根据睡眠质量评分,被归类为“睡眠差”的个体的孤独感评分明显高于“睡眠好”的个体。然而,睡眠呼吸暂停组和无睡眠呼吸暂停组之间的总孤独感评分没有显著差异。我们发现,较高的孤独感与较低的习惯性睡眠效率和睡眠时间显著相关,并且还受到睡眠药物使用的影响。我们的研究结果表明,孤独感的增加与主观睡眠质量较差有关,但与睡眠呼吸暂停无关。这些研究结果表明,针对孤独感和睡眠质量的综合干预措施可能对老年女性很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/71602462ef09/10.1177_00914150241255888-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/c0182e992d12/10.1177_00914150241255888-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/4acdc72720b4/10.1177_00914150241255888-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/152404b7e3a2/10.1177_00914150241255888-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/6d47ea9ffc01/10.1177_00914150241255888-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/71602462ef09/10.1177_00914150241255888-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/c0182e992d12/10.1177_00914150241255888-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/4acdc72720b4/10.1177_00914150241255888-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/152404b7e3a2/10.1177_00914150241255888-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/6d47ea9ffc01/10.1177_00914150241255888-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/72bc/11490093/71602462ef09/10.1177_00914150241255888-fig5.jpg

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本文引用的文献

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