全球 1990 年至 2019 年青少年 2 型糖尿病负担。

Global burden of type 2 diabetes in adolescents from 1990 to 2019.

机构信息

Department of Endocrinology, Hunan Provincial People's Hospital, The First Affiliated Hospital of Hunan Normal University, Changsha, China.

出版信息

Front Endocrinol (Lausanne). 2024 Jul 11;15:1405739. doi: 10.3389/fendo.2024.1405739. eCollection 2024.

DOI:10.3389/fendo.2024.1405739

PMID:39055060

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11269148/

Abstract

PURPOSE

To evaluate the burden of type 2 diabetes (T2D) among adolescents (15-24 years old) from 1990 to 2019.

METHODS

The age-standardized incidence rate (ASIR) and disability-adjusted life years (DALYs) rate of adolescents were analyzed according to age, sex, geographical location, and sociodemographic index (SDI). The estimated annual percentage change (EAPC) was estimated to quantify the trends.

RESULTS

From 1990 to 2019, the ASIR (EAPC = 1.07) and age-standardized DALY rate (EAPC = 2.01) of T2D in adolescents showed an increasing trend. The ASIR was higher in males than in females. The burden was greater in the 20-24-year age group. Of the five SDI regions, the highest ASIR and age-standardized DALY rate were found in low-middle-SDI regions, while the greatest increase in these rates was observed in high-SDI regions (EAPC = 3.28 and 3.55, respectively). Of the 21 regions analyzed, the highest ASIR and age-standardized DALY rate were found in Oceania. Of the 204 countries analyzed, the Marshall Islands (651.16) and Kiribati (277.42) had the highest ASIR and DALYs, respectively. The regions with the greatest increase in the ASIR from 1990 to 2019 were Western Europe (EAPC = 4.15), high-income North America (EAPC = 4.72).

CONCLUSIONS

The global burden of T2D in adolescents showed an overall upward trend from 1990 to 2019. It is necessary to strengthen prevention measures related to risk factors for T2D among young people, especially in areas with a low-to-medium SDI.

摘要

目的

评估 1990 年至 2019 年期间青少年（15-24 岁）2 型糖尿病（T2D）的负担。

方法

根据年龄、性别、地理位置和社会人口指数（SDI）分析青少年的年龄标准化发病率（ASIR）和残疾调整生命年（DALY）率。采用估计年度百分比变化（EAPC）来量化趋势。

结果

从 1990 年到 2019 年，青少年 T2D 的 ASIR（EAPC=1.07）和年龄标准化 DALY 率（EAPC=2.01）呈上升趋势。男性的 ASIR 高于女性。20-24 岁年龄组的负担更大。在五个 SDI 区域中，中低 SDI 区域的 ASIR 和年龄标准化 DALY 率最高，而这些率的增长最大的是高 SDI 区域（EAPC=3.28 和 3.55）。在分析的 21 个区域中，大洋洲的 ASIR 和年龄标准化 DALY 率最高。在所分析的 204 个国家中，马绍尔群岛（651.16）和基里巴斯（277.42）的 ASIR 和 DALY 最高。从 1990 年到 2019 年，ASIR 增长率最高的地区是西欧（EAPC=4.15）和高收入北美（EAPC=4.72）。