Mostafiz Md Munir, Hwang Hwal-Su, Kim Jun-Ran, Kim Bong-Su, Lee Kyeong-Yeoll
Department of Plant Medicine, College of Agriculture and Life Sciences, Kyungpook National University, Daegu 41566, Republic of Korea.
Institute of Agricultural Science and Technology, Kyungpook National University, Daegu 41566, Republic of Korea.
Insects. 2024 Jun 27;15(7):477. doi: 10.3390/insects15070477.
Phosphine (PH) has been widely used as a fumigant in food storage, but increasing PH resistance in major pests makes finding alternative fumigants urgent. Methyl benzoate (MBe), a volatile organic compound regarded to be a food-safe natural product, has recently demonstrated significant toxicity against a variety of insect pests. This study is the first evaluation of the fumigation toxicity of three benzoate compounds, MBe, vinyl benzoate, and ethyl benzoate, against PH-susceptible and PH-resistant strains of and . All strains were exposed to the compounds at concentrations up to 20 µL/1.5 L air for 24 h. Compared to vinyl benzoate and ethyl benzoate, MBe induced higher mortality rates in all strains at all concentrations. When food was made available, the lethal median concentration for MBe was 10-17-fold higher than when tested without food. Moreover, no significant differences were observed between the responses of the PH-susceptible and PH-resistant strains to the compounds. Notably, was more susceptible to MBe. In laboratory settings, MBe successfully controlled PH-resistant strains of and , making it a viable option for PH-resistance management. Thus, MBe might be suitable for food security programs as an environmentally benign alternative fumigant.
磷化氢（PH）已被广泛用作粮食储存中的熏蒸剂，但主要害虫对PH的抗性不断增强，使得寻找替代熏蒸剂变得紧迫。苯甲酸甲酯（MBe）是一种挥发性有机化合物，被认为是一种食品安全的天然产物，最近已证明对多种害虫具有显著毒性。本研究首次评估了三种苯甲酸酯化合物，即MBe、苯甲酸乙烯酯和苯甲酸乙酯，对PH敏感和PH抗性品系的熏蒸毒性。所有品系都在浓度高达20 µL/1.5 L空气的条件下暴露于这些化合物中24小时。与苯甲酸乙烯酯和苯甲酸乙酯相比，MBe在所有浓度下对所有品系都诱导了更高的死亡率。当提供食物时，MBe的致死中浓度比无食物测试时高10 - 17倍。此外，PH敏感和PH抗性品系对这些化合物的反应之间未观察到显著差异。值得注意的是，[此处原文缺失具体物种名称]对MBe更敏感。在实验室环境中，MBe成功地控制了[此处原文缺失具体物种名称]的PH抗性品系，使其成为PH抗性管理的一个可行选择。因此，MBe作为一种环境友好的替代熏蒸剂可能适用于粮食安全计划。
