Modrzejewska Monika, Zdanowska Oliwia, Świstara Dawid, Połubiński Piotr
2nd Department of Ophthalmology, Pomeranian Medical University in Szczecin, Powstańców Wielkopolskich 72, 70-111 Szczecin, Poland.
K. Marcinkowski University Hospital in Zielona Góra, 65-046 Zielona Góra, Poland.
Children (Basel). 2024 Jun 25;11(7):769. doi: 10.3390/children11070769.
Uveitis is an inflammatory disease that can lead to severe complications, including vision loss. The pediatric population is particularly at risk of developing complications, as uveitis in this age group often has idiopathic origins or is associated with systemic diseases that follow a severe course. This, coupled with unfavorable treatment outcomes, continues to be a challenge in pediatric ophthalmology. The cornerstone of uveitis treatment involves a therapeutic strategy that depends on the etiology, severity, and localization of the inflammation, as well as the patient's response to treatment and the presence of ocular complications. Patients who do not receive timely treatment face a significantly increased risk of experiencing a severe disease course. Understanding potential therapeutic options and their side effects is crucial in managing children with uveitis. Equally important is the continuous monitoring of the child's condition throughout the treatment process, due to the chronic and recurrent nature of uveitis in this demographic. The authors conducted a review of the current literature from 2018 to 2023 on the management and introduction of new therapeutic approaches for children with uveitis.
葡萄膜炎是一种炎症性疾病，可导致包括视力丧失在内的严重并发症。儿童群体尤其容易出现并发症，因为该年龄组的葡萄膜炎通常起源不明或与病情严重的全身性疾病有关。再加上治疗效果不佳，这仍然是小儿眼科面临的一项挑战。葡萄膜炎治疗的基石是一种治疗策略，该策略取决于炎症的病因、严重程度和部位，以及患者对治疗的反应和眼部并发症的存在。未及时接受治疗的患者经历严重病程的风险会显著增加。了解潜在的治疗选择及其副作用对于管理患有葡萄膜炎的儿童至关重要。同样重要的是，由于该人群中葡萄膜炎具有慢性和复发性，在整个治疗过程中持续监测儿童的病情。作者对2018年至2023年期间关于儿童葡萄膜炎管理和新治疗方法引入的现有文献进行了综述。
