儿童结核病。
Tuberculosis in Children.
机构信息
Division of Pediatric Infectious Diseases, University of California, San Francisco, 1001 Potrero Avenue, Building 3, Room 635A, Box 1234, San Francisco, CA 94110, USA.
Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, 200 N. Wolfe Street, Room 3150, Baltimore, MD 21287, USA.
出版信息
Infect Dis Clin North Am. 2022 Mar;36(1):49-71. doi: 10.1016/j.idc.2021.11.008.
Abstract
Tuberculosis (TB) is one of the leading causes of mortality in children worldwide, but there remain significant challenges in diagnosing and treating TB infection and disease. Treatment of TB infection in children and adolescents is critical to prevent progression to TB disease and to prevent them from becoming the future reservoir for TB transmission. This article reviews the clinical approach to diagnosing and treating latent TB infection and pulmonary and extrapulmonary TB disease in children. Also discussed are emerging diagnostics and therapeutic regimens that aim to improve pediatric TB detection and outcomes.
摘要
结核病（TB）是全球导致儿童死亡的主要原因之一，但在诊断和治疗结核病感染和疾病方面仍存在重大挑战。治疗儿童和青少年的结核病感染对于预防结核病进展和防止其成为未来结核病传播的储主至关重要。本文综述了诊断和治疗儿童潜伏性结核病感染以及肺外和肺内结核病的临床方法。还讨论了旨在提高儿科结核病检测和结果的新出现的诊断和治疗方案。
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