Mediterranean Food By-products as a Valuable Source of Bioactive Compounds with Health Properties.

Recently, considerable attention has been focused on the recovery and re-use of waste plant matrices as promising sources of bioactive compounds with health effects. As the Mediterranean diet involves the consumption of great amounts of fruits and vegetables, large quantities of agro-food by-products are generated, causing economic and environmental problems. Such by-products contain a great variety of bioactive compounds whose potential health benefits include anti-inflammatory, antioxidant, anti-- cancer, antimicrobial, hypoglycemic, antidepressant, cardio- and neuro-protective activities. Therefore, in this review, by-products from the most common fruits and vegetables processed in the Mediterranean area, such as tomato, olive, citrus fruit, almond, pomegranate, carob, date, and grape, were taken into account, pointing out the content of bioactive ingredients in extracts obtained from different parts of plants, fruits, and vegetables. Furthermore, studies performed to assess the beneficial effects of extracts obtained from Mediterranean agro-food by-products were reviewed, highlighting the potential benefits of waste plant matrices re-usage in the pharmaceutical, nutraceutical, and cosmetic fields.