Liu Jia-Hui, Dhamija Gaurav, Jiang Yi, He Dan, Zhou Xiao-Cong
Department of Urology, The Dingli Clinical College of Wenzhou Medical University (Wenzhou Central Hospital), Wenzhou 325000, Zhejiang Province, China.
School of International Studies, Wenzhou Medical University, Wenzhou Central Hospital, Wenzhou 325000, Zhejiang Province, China.
World J Gastrointest Oncol. 2024 Jul 15;16(7):3331-3340. doi: 10.4251/wjgo.v16.i7.3331.
Metastatic breast cancer originating in the gastrointestinal tract is a rare occurrence. The limited number of cases has resulted in incomplete understanding of the disease, making it challenging to differentiate from primary breast cancer. While clinical history and immunohistochemical studies can aid in distinguishing between the two, the management principles and pathogenesis of gastrointestinal metastatic breast cancer remain controversial. The scarcity of data has hampered comprehensive knowledge. Our objective is to shed light on this rare disease through our case study.
Here, we report a case of breast metastasis from gastric cancer in a 43-year-old woman. This patient was admitted to our hospital with complaints of discomfort in the upper and middle abdomen persisting for two months, as well as black stools for over ten days. She underwent radical distal gastrectomy for gastric cancer, followed by postoperative chemotherapy. Three years later, the patient developed bilateral breast nodules. Imaging studies indicated a high probability of malignancy. She subsequently underwent a right modified radical mastectomy and excision of a left breast mass. Postoperative pathology revealed the right breast tumor was consistent with primary gastric cancer.
We present a case of breast metastasis from gastric cancer to contribute to the limited foundation of research into this rare disease.
起源于胃肠道的转移性乳腺癌极为罕见。病例数量有限导致对该疾病的认识不完整,使其难以与原发性乳腺癌区分开来。虽然临床病史和免疫组化研究有助于区分两者,但胃肠道转移性乳腺癌的治疗原则和发病机制仍存在争议。数据的匮乏阻碍了全面的了解。我们的目的是通过我们的病例研究来阐明这种罕见疾病。
在此,我们报告一例43岁女性胃癌转移至乳腺的病例。该患者因中上腹不适持续两个月及黑便十余天入院。她接受了远端胃癌根治术,随后进行了术后化疗。三年后,患者出现双侧乳腺结节。影像学检查显示恶性可能性高。她随后接受了右改良根治性乳房切除术及左乳肿块切除术。术后病理显示右乳肿瘤与原发性胃癌一致。
我们报道了一例胃癌转移至乳腺的病例,以补充对这种罕见疾病的有限研究基础。