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复合伤的研究,第26篇通讯:亚致死剂量全身照射后抵抗力状态变化的研究(作者译)

[Investigations on combined injuries, 26th communication: investigations on the changes in the state of resistance following sublethal whole-body irradiation (author's transl)].

作者信息

Schick P, Werdan K, Baljer G, Sailer A

出版信息

Strahlentherapie. 1979 Dec;155(12):849-55.

PMID:390775
Abstract

The risk of a bacterial invasion by pseudomonas, e. coli, proteus, citrobacter and gaffkya via an open skin wound was investigated in combined injured mice (infliction of a skin wound and irradiations). Suspensions of different bacterial strains were applied on the wound and then the lethality was determined. Besides of apathogenic (citrobacter, proteus, gaffkya) and high pathogenic bacteria (e. coli and pseudomonas) an e. coli strain of the 0-Group 81 was found that seems to induce a decrease of lethality even after sublethal whole body irradiation.

摘要

在复合伤小鼠(造成皮肤伤口并进行照射)中,研究了铜绿假单胞菌、大肠杆菌、变形杆菌、柠檬酸杆菌和加夫基氏菌通过开放性皮肤伤口进行细菌侵袭的风险。将不同菌株的悬浮液涂抹在伤口上,然后测定致死率。除了无致病性的(柠檬酸杆菌、变形杆菌、加夫基氏菌)和高致病性细菌(大肠杆菌和铜绿假单胞菌)外,还发现了一种81群大肠杆菌菌株,即使在亚致死性全身照射后,它似乎也能降低致死率。

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