Wustrow T, Werner G T, Wagner M, Messerschmidt O
Strahlentherapie. 1980 Feb;156(2):139-42.
A combined traumatism adversely affects radiation disease. Therefore it was of interest to investigate what influence exerts a combined lesion on an existing immunity state. After whole-body irradiation alone as well as after combined irradiation and traumatism, no significant decrease of the antibody level was found in rabbits which had been infected with vaccina virus Elstree four weeks before the irradiation. The conclusion seems justified that patients submitted to a therapeutic immunosuppression have to be vaccinated against dangerous virus infections before and that a natural immunity or an immunity induced by vaccination cannot be destroyed even by an accident involving a high radiation exposure.
复合创伤对放射病有不利影响。因此,研究复合损伤对现有免疫状态有何种影响很有意义。在单独全身照射以及照射与创伤复合作用后,在照射前四周感染了伊斯特里牛痘病毒的兔子中,未发现抗体水平有显著下降。似乎有理由得出这样的结论:接受治疗性免疫抑制的患者必须在之前接种针对危险病毒感染的疫苗,而且即使遭遇高辐射暴露的事故,天然免疫或疫苗诱导的免疫也不会被破坏。