Kim Hack-Lyoung
Division of Cardiology, Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul National University College of Medicine, 07061 Seoul, Republic of Korea.
Rev Cardiovasc Med. 2024 Jan 8;25(1):7. doi: 10.31083/j.rcm2501007. eCollection 2024 Jan.
Clinically assessing arterial stiffness is valuable because it aids in predicting future cardiovascular events. There are several methods for measuring arterial stiffness, including pulse wave velocity (PWV), augmentation index, and pulse pressure. Numerous studies have shown that these indicators of arterial stiffness possess prognostic value for various patient groups as well as the general population. In cross-sectional studies, arterial stiffness was also linked to organ damage indices. However, most studies related to arterial stiffness have relied on a single measurement. Taking multiple serial measurements of arterial stiffness offers several advantages. Through repeated assessments, one can confirm the variability of arterial stiffness and observe changes over time, which is beneficial for understanding its pathophysiology. Such repeated measurements are also invaluable in evaluating the efficacy of interventions aimed at improving arterial stiffness. However, caution is needed, as there is no standardized method for measuring arterial stiffness. For instance, with PWV, the values can be influenced by numerous external factors. Therefore, the external conditions during the measurement must be noted. It's essential to recognize the pros and cons of repeated arterial stiffness measurements and integrate them effectively into clinical practice.
临床评估动脉僵硬度很有价值，因为它有助于预测未来的心血管事件。测量动脉僵硬度有多种方法，包括脉搏波速度（PWV）、增强指数和脉压。大量研究表明，这些动脉僵硬度指标对不同患者群体以及普通人群都具有预后价值。在横断面研究中，动脉僵硬度还与器官损伤指标相关。然而，大多数与动脉僵硬度相关的研究都依赖于单次测量。多次连续测量动脉僵硬度有几个优点。通过重复评估，可以确认动脉僵硬度的变异性并观察其随时间的变化，这有助于理解其病理生理学。这种重复测量在评估旨在改善动脉僵硬度的干预措施的疗效方面也非常宝贵。然而，需要谨慎，因为目前尚无测量动脉僵硬度的标准化方法。例如，对于PWV，其值会受到许多外部因素的影响。因此，测量期间的外部条件必须记录下来。必须认识到重复测量动脉僵硬度的利弊，并有效地将其纳入临床实践。
