吸入性酸对呼吸道防御机制的影响。
Effects of inhaled acids on respiratory tract defense mechanisms.
作者信息
Schlesinger R B
出版信息
Environ Health Perspect. 1985 Nov;63:25-38. doi: 10.1289/ehp.856325.
Abstract
The respiratory tract is endowed with an interlocking array of nonspecific and specific defense mechanisms which protect it from the effects of inhaled microbes and toxicants, and reduce the risk of absorption of materials into the bloodstream, with subsequent systemic translocation. Ambient acids may compromise these defenses, perhaps providing a link between exposure and development of chronic and acute pulmonary disease. This paper reviews the effects of inhaled acids upon the nonspecific clearance system of the lungs.
摘要
呼吸道具有一系列相互关联的非特异性和特异性防御机制，这些机制可保护其免受吸入微生物和有毒物质的影响，并降低物质吸收进入血液继而发生全身转移的风险。环境中的酸可能会损害这些防御功能，这或许为暴露与急慢性肺部疾病的发生之间提供了一种联系。本文综述了吸入酸对肺部非特异性清除系统的影响。
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