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1
Effects of inhaled acids on respiratory tract defense mechanisms.吸入性酸对呼吸道防御机制的影响。
Environ Health Perspect. 1985 Nov;63:25-38. doi: 10.1289/ehp.856325.
2
Methods for evaluating the toxicological effects of gaseous and particulate contaminants on pulmonary microbial defense systems.评估气态和颗粒污染物对肺部微生物防御系统毒理学效应的方法。
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4
[Respiratory tract and the process of removing dust].[呼吸道与除尘过程]
Med Lav. 1984 Jan-Feb;75(1):7-19.
5
Effects of airborne pollutants on mucociliary clearance.空气传播污染物对黏液纤毛清除功能的影响。
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6
The regional deposition of inhaled aerosols in man.人体吸入气溶胶的区域沉积情况。
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7
[Principal mechanisms of defense of the respiratory system against pollution].[呼吸系统抵御污染的主要防御机制]
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8
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9
The effects of selected air pollutants on clearance of titanic oxide particles from the lungs of rats.选定空气污染物对大鼠肺部二氧化钛颗粒清除的影响。
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10
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Acute and 28-Day Repeated Inhalation Toxicity Study of Glycolic Acid in Male Sprague-Dawley Rats.乙二醇酸在雄性 Sprague-Dawley 大鼠中的急性和 28 天重复吸入毒性研究。
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Pulmonary response after exposure to inhaled nickel hydroxide nanoparticles: short and long-term studies in mice.吸入氢氧化镍纳米颗粒后的肺部反应：小鼠短期和长期研究
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Environ Health Perspect. 2005 Nov;113(11):1575-9. doi: 10.1289/ehp.8091.
5
Effects of inhaled acid aerosols on lung mechanics: an analysis of human exposure studies.吸入酸性气溶胶对肺力学的影响：人体暴露研究分析
Environ Health Perspect. 1985 Nov;63:39-44. doi: 10.1289/ehp.856339.
6
Incidence of laryngeal cancer and exposure to acid mists.喉癌发病率与酸性雾气暴露情况
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7
Reexamination of London, England, mortality in relation to exposure to acidic aerosols during 1963-1972 winters.对1963 - 1972年冬季英国伦敦与酸性气溶胶暴露相关的死亡率的重新审视。
Environ Health Perspect. 1989 Feb;79:73-82. doi: 10.1289/ehp.897973.

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[ON THE PHYSICAL-CHEMICAL BEHAVIOR OF THE NASAL MUCUS].[论鼻黏液的物理化学行为]
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INTERACTION OF RESPIRATORY EPITHELIUM OF THE CHICK AND NEWCASTLE DISEASE VIRUS.鸡呼吸道上皮与新城疫病毒的相互作用
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The chemical characterization of human tracheobronchial secretion: a possible clue to the orgin of fibrocystic mucus.人类气管支气管分泌物的化学特性：纤维囊性黏液起源的一个可能线索。
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Ciliary streaming in the bronchial tree and the time element in carcinogenesis.支气管树中的纤毛运动与致癌作用中的时间因素。
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Induction of bronchial cancer by local massing of carcinogen concentrate in outdrifting mucus.在外流黏液中致癌物浓缩物局部聚集诱发支气管癌。
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Effects of sulfate aerosols in combination with ozone on elimination of tracer particles inhaled by rats.硫酸盐气溶胶与臭氧共同作用对大鼠吸入示踪颗粒清除的影响。
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Impaired mucociliary transport as a pathogenetic factor in obstructive pulmonary diseases.黏液纤毛运输受损作为阻塞性肺疾病的一个致病因素。
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吸入性酸对呼吸道防御机制的影响。

Effects of inhaled acids on respiratory tract defense mechanisms.

作者信息

Schlesinger R B

出版信息

Environ Health Perspect. 1985 Nov;63:25-38. doi: 10.1289/ehp.856325.

DOI:10.1289/ehp.856325
PMID:3908089
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1568494/
Abstract

The respiratory tract is endowed with an interlocking array of nonspecific and specific defense mechanisms which protect it from the effects of inhaled microbes and toxicants, and reduce the risk of absorption of materials into the bloodstream, with subsequent systemic translocation. Ambient acids may compromise these defenses, perhaps providing a link between exposure and development of chronic and acute pulmonary disease. This paper reviews the effects of inhaled acids upon the nonspecific clearance system of the lungs.

摘要

呼吸道具有一系列相互关联的非特异性和特异性防御机制，这些机制可保护其免受吸入微生物和有毒物质的影响，并降低物质吸收进入血液继而发生全身转移的风险。环境中的酸可能会损害这些防御功能，这或许为暴露与急慢性肺部疾病的发生之间提供了一种联系。本文综述了吸入酸对肺部非特异性清除系统的影响。