肝移植排斥反应病例的活检结果。
Biopsy findings in cases of rejection of liver allograft.
作者信息
Hubscher S G, Clements D, Elias E, McMaster P
出版信息
J Clin Pathol. 1985 Dec;38(12):1366-73. doi: 10.1136/jcp.38.12.1366.
Abstract
Features of rejection were found in 21 needle biopsies obtained from seven patients after liver transplantation. Wedge biopsies taken peroperatively were used as a baseline for comparison. Rejection was diagnosed by excluding other known causes of graft dysfunction using appropriate methods. In cases in which these criteria were fulfilled a consistent picture of rejection was seen, and this was useful in clinical management. Two features constantly present in cases of acute rejection were: a dense mixed portal inflammatory infiltrate; and polymorphonuclear infiltration of biliary epithelium.
摘要
在7例肝移植患者的21次经皮肝穿刺活检中发现了排斥反应的特征。术中获取的楔形活检标本用作比较的基线。通过使用适当方法排除其他已知的移植物功能障碍原因来诊断排斥反应。在满足这些标准的病例中，可以看到一致的排斥反应表现，这对临床管理很有用。急性排斥反应病例中始终存在的两个特征是：密集的混合性门静脉炎性浸润；以及胆管上皮的多形核浸润。
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