• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

相似文献

1
Herbal and Natural Supplements for Improving Sleep: A Literature Review.用于改善睡眠的草药和天然补充剂:文献综述
Psychiatry Investig. 2024 Aug;21(8):810-821. doi: 10.30773/pi.2024.0121. Epub 2024 Aug 2.
2
Valerian-hops combination and diphenhydramine for treating insomnia: a randomized placebo-controlled clinical trial.缬草-啤酒花组合与苯海拉明治疗失眠:一项随机安慰剂对照临床试验
Sleep. 2005 Nov;28(11):1465-71. doi: 10.1093/sleep/28.11.1465.
3
Oral nonprescription treatment for insomnia: an evaluation of products with limited evidence.失眠的口服非处方治疗:对证据有限的产品的评估
J Clin Sleep Med. 2005 Apr 15;1(2):173-87.
4
An internet-based randomized, placebo-controlled trial of kava and valerian for anxiety and insomnia.一项基于网络的关于卡瓦根和缬草治疗焦虑和失眠的随机、安慰剂对照试验。
Medicine (Baltimore). 2005 Jul;84(4):197-207. doi: 10.1097/01.md.0000172299.72364.95.
5
Nutraceuticals for Sleep Disorders.用于睡眠障碍的营养保健品。
Comb Chem High Throughput Screen. 2021 Sep 14;24(10):1583-1592. doi: 10.2174/1386207324666210121111446.
6
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.研究补充镁对自我报告的焦虑和睡眠质量的影响:一项系统综述。
Cureus. 2024 Apr 29;16(4):e59317. doi: 10.7759/cureus.59317. eCollection 2024 Apr.
7
Nutritional and herbal supplements for anxiety and anxiety-related disorders: systematic review.焦虑和焦虑相关障碍的营养和草本补充剂:系统评价。
Nutr J. 2010 Oct 7;9:42. doi: 10.1186/1475-2891-9-42.
8
Herbal medicine for insomnia: A systematic review and meta-analysis.草药治疗失眠:系统评价和荟萃分析。
Sleep Med Rev. 2015 Dec;24:1-12. doi: 10.1016/j.smrv.2014.12.003. Epub 2014 Dec 17.
9
Safety and efficacy of herbal sedatives in cancer care.草药镇静剂在癌症护理中的安全性和有效性。
Integr Cancer Ther. 2004 Jun;3(2):128-48. doi: 10.1177/1534735404265003.
10
Dietary supplements used in the treatment of depression, anxiety, and sleep disorders.用于治疗抑郁症、焦虑症和睡眠障碍的膳食补充剂。
Lippincotts Prim Care Pract. 1999 May-Jun;3(3):290-304.

引用本文的文献

1
Effects of Chronic Administration of a Standardized Rice Bran Supplement on Sleep Architecture and Profiles in Mice: A Comparative Study with a Hypnotic Drug Zolpidem.长期给予标准化米糠补充剂对小鼠睡眠结构和特征的影响:与催眠药物唑吡坦的比较研究。
J Microbiol Biotechnol. 2025 Aug 26;35:e2505010. doi: 10.4014/jmb.2505.05010.
2
Lemon Verbena Extract Enhances Sleep Quality and Duration via Modulation of Adenosine A1 and GABA Receptors in Pentobarbital-Induced and Polysomnography-Based Sleep Models.柠檬马鞭草提取物通过调节戊巴比妥诱导的和基于多导睡眠图的睡眠模型中的腺苷A1和GABA受体来提高睡眠质量和时长。
Int J Mol Sci. 2025 Jun 14;26(12):5723. doi: 10.3390/ijms26125723.
3
Integrative sleep management: from molecular pathways to conventional and herbal treatments.综合睡眠管理:从分子途径到传统与草药治疗
Naunyn Schmiedebergs Arch Pharmacol. 2025 May 8. doi: 10.1007/s00210-025-04183-y.
4
Commonly Used Dose of Montmorency Tart Cherry Powder Does Not Improve Sleep or Inflammation Outcomes in Individuals with Overweight or Obesity.常用剂量的蒙特莫伦西酸樱桃粉并不能改善超重或肥胖个体的睡眠或炎症指标。
Nutrients. 2024 Nov 28;16(23):4125. doi: 10.3390/nu16234125.

本文引用的文献

1
An Updated Review of the Genus : A Valuable Source of Bioactive Compounds for Health and Disease Prevention.该属的最新综述:健康与疾病预防生物活性化合物的宝贵来源。
Plants (Basel). 2022 Dec 8;11(24):3434. doi: 10.3390/plants11243434.
2
The impact of tryptophan supplementation on sleep quality: a systematic review, meta-analysis, and meta-regression.色氨酸补充对睡眠质量的影响:系统评价、荟萃分析和荟萃回归。
Nutr Rev. 2022 Jan 10;80(2):306-316. doi: 10.1093/nutrit/nuab027.
3
Humulone Modulation of GABA Receptors and Its Role in Hops Sleep-Promoting Activity.蛇麻酮对γ-氨基丁酸受体的调节作用及其在啤酒花助眠活性中的作用。
Front Neurosci. 2020 Oct 14;14:594708. doi: 10.3389/fnins.2020.594708. eCollection 2020.
4
Valerian Root in Treating Sleep Problems and Associated Disorders-A Systematic Review and Meta-Analysis.缬草根治疗睡眠问题及相关疾病的系统评价和荟萃分析。
J Evid Based Integr Med. 2020 Jan-Dec;25:2515690X20967323. doi: 10.1177/2515690X20967323.
5
Hops compounds modulatory effects and 6-prenylnaringenin dual mode of action on GABA receptors.啤酒花化合物对 GABA 受体的调制作用和 6- 香叶基柚皮素的双重作用模式。
Eur J Pharmacol. 2020 Apr 15;873:172962. doi: 10.1016/j.ejphar.2020.172962. Epub 2020 Jan 27.
6
Adverse Events Associated with Melatonin for the Treatment of Primary or Secondary Sleep Disorders: A Systematic Review.褪黑素治疗原发性或继发性睡眠障碍相关不良事件的系统评价。
CNS Drugs. 2019 Dec;33(12):1167-1186. doi: 10.1007/s40263-019-00680-w.
7
GABA and l-theanine mixture decreases sleep latency and improves NREM sleep.GABA 和 l-茶氨酸的混合物可减少睡眠潜伏期并改善 NREM 睡眠。
Pharm Biol. 2019 Dec;57(1):65-73. doi: 10.1080/13880209.2018.1557698.
8
Analysis, Nutrition, and Health Benefits of Tryptophan.色氨酸的分析、营养及健康益处
Int J Tryptophan Res. 2018 Sep 26;11:1178646918802282. doi: 10.1177/1178646918802282. eCollection 2018.
9
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.镁摄入量与睡眠障碍症状:来自江苏省成年人五年随访的营养研究结果。
Nutrients. 2018 Sep 21;10(10):1354. doi: 10.3390/nu10101354.
10
Magnesium and Human Health: Perspectives and Research Directions.镁与人类健康:观点与研究方向
Int J Endocrinol. 2018 Apr 16;2018:9041694. doi: 10.1155/2018/9041694. eCollection 2018.

用于改善睡眠的草药和天然补充剂:文献综述

Herbal and Natural Supplements for Improving Sleep: A Literature Review.

作者信息

Yeom Ji Won, Cho Chul-Hyun

机构信息

Department of Psychiatry, Korea University College of Medicine, Seoul, Republic of Korea.

出版信息

Psychiatry Investig. 2024 Aug;21(8):810-821. doi: 10.30773/pi.2024.0121. Epub 2024 Aug 2.

DOI:10.30773/pi.2024.0121
PMID:39086164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11321869/
Abstract

OBJECTIVE

Herbal and natural supplements have gained popularity as alternative treatments to insomnia and sleep disorders due to their perceived safety and potential effectiveness. This literature review summarizes the current evidence on the efficacy, safety, and mechanisms of action of commonly used supplements for sleep, including valerian, hops, kava, German chamomile, cherry, tryptophan, theanine, melatonin, magnesium, and zinc.

METHODS

We conducted literature review of clinical research on herbal and supplements for sleep reported to date. We summarized key findings and reviewed outcomes related to clinical efficacy and side effects.

RESULTS

Findings suggest that certain supplements, particularly valerian, hops, and melatonin, could be effective in improving sleep quality and reducing insomnia symptoms through modulation of neurotransmitter systems and regulation of sleep-wake cycles. However, the strength of the evidence varies with unestablished optimal dosages, formulations, and treatment durations. Although generally considered safe, these supplements are not without risks, such as rare but serious adverse effects associated with kava and potential interactions with prescription medications. The quality and purity of supplements also vary widely due to a lack of strict regulations.

CONCLUSION

Healthcare providers should remain informed about the latest research and work closely with patients to develop personalized treatment plans. Herbal and natural supplements may offer promising alternatives or adjunct treatments for insomnia and sleep disorders, but their use should be guided by the best available evidence and individual patient requirements. Larger, well-designed clinical trials are needed to establish the efficacy and safety of these supplements for clinical decision-making.

摘要

目的

草药和天然补充剂因其被认为的安全性和潜在有效性,作为失眠和睡眠障碍的替代疗法而受到欢迎。这篇文献综述总结了目前关于常用睡眠补充剂(包括缬草、啤酒花、卡瓦、德国洋甘菊、樱桃、色氨酸、茶氨酸、褪黑素、镁和锌)的疗效、安全性及作用机制的证据。

方法

我们对迄今报道的关于草药和睡眠补充剂的临床研究进行了文献综述。我们总结了主要发现,并回顾了与临床疗效和副作用相关的结果。

结果

研究结果表明,某些补充剂,特别是缬草、啤酒花和褪黑素,可能通过调节神经递质系统和调节睡眠-觉醒周期来有效改善睡眠质量并减轻失眠症状。然而,证据的力度因未确定的最佳剂量、配方和治疗持续时间而有所不同。尽管通常被认为是安全的,但这些补充剂并非没有风险,例如与卡瓦相关的罕见但严重的不良反应以及与处方药的潜在相互作用。由于缺乏严格监管,补充剂的质量和纯度也存在很大差异。

结论

医疗保健提供者应了解最新研究,并与患者密切合作制定个性化治疗方案。草药和天然补充剂可能为失眠和睡眠障碍提供有前景的替代或辅助治疗方法,但它们的使用应以现有最佳证据和个体患者需求为指导。需要进行更大规模、设计良好的临床试验来确定这些补充剂在临床决策中的疗效和安全性。