Pei Hang, Zhang Yi, Wang Chao, He Bang-Jian
The First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053, Zhejiang Province, China.
Department of Orthopaedics, Anji County Hospital of Chinese Medicine, Anji 313300, Zhejiang Province, China.
World J Stem Cells. 2024 Jul 26;16(7):739-741. doi: 10.4252/wjsc.v16.i7.739.
Recently, we read an article published by the Yang . The results of this study indicated that engineered exosomes loaded with microRNA-29a (miR-29a) alleviate knee inflammation and maintain extracellular matrix stability in Sprague Dawley rats. The study's results provide useful information for treating knee osteoarthritis (KOA). This letter, shares our perspectives on treating KOA using engineered exosomes for miR-29a.
最近，我们阅读了杨发表的一篇文章。该研究结果表明，装载有微小RNA-29a（miR-29a）的工程化外泌体可减轻Sprague Dawley大鼠的膝关节炎症并维持细胞外基质稳定性。该研究结果为治疗膝关节骨关节炎（KOA）提供了有用的信息。这封信分享了我们对于使用装载miR-29a的工程化外泌体治疗KOA的观点。
