Güneysu Physical Therapy and Rehabilitation College, Recep Tayyip Erdogan University, Rize, Turkey.
Department of Internal Medicine, Faculty of Medicine, Bakircay University, Izmir, Turkey.
Medicine (Baltimore). 2024 Aug 2;103(31):e39031. doi: 10.1097/MD.0000000000039031.
This study aimed to compare the acute effects of aerobic exercise performed with blood flow restriction (BFR), a novel method to increase exercise gains, with blood free flow (BFF) conditions in type 2 diabetes mellitus (T2DM).
Fifteen individuals with T2DM performed BFF and BFR (40% of arterial occlusion pressure) cycling exercises 48 hours apart, at equal intensity (45% heart rate reserve) and duration (38 minutes). Systolic blood pressure (SBP), diastolic blood pressure (DBP), mean arterial pressure (MAP), blood glucose, heart rate, and muscle oxygen saturation (SmO2) were assessed before-after and during exercise sessions.
SBP, DBP, and MAP in the overload phase were higher in the BFR group than in the BFF group (P = .009, 0.031, and 0.013, respectively). Changes in blood pressure (∆SBP and ∆DBP) were similar between the BFF and BFR groups (P > .05), whereas ∆MAP differed (P = .016). Changes in blood glucose levels and heart rates were not significantly different between the groups. Although SmO2baseline was lower in the BFR group (P = .049), SmO2min and SmO2max did not differ significantly between the BFF and BFR groups.
The similar decrease in blood glucose levels between the groups suggests that BFR exercise is favorable in terms of hypoglycemia. The higher blood pressure observed during the BFR exercise remained within safe limits. These results suggest that people with T2DM can safely perform BFR aerobic exercises; however, further studies are required.
本研究旨在比较血流限制(BFR)与血液自由流动(BFF)两种方法对 2 型糖尿病(T2DM)患者急性运动效果的影响。
15 名 T2DM 患者分别在相隔 48 小时的情况下进行 BFF 和 BFR(动脉闭塞压的 40%)自行车运动,运动强度(心率储备的 45%)和时间(38 分钟)保持一致。在运动前后和运动期间评估收缩压(SBP)、舒张压(DBP)、平均动脉压(MAP)、血糖、心率和肌肉氧饱和度(SmO2)。
在超负荷阶段,BFR 组的 SBP、DBP 和 MAP 均高于 BFF 组(P=0.009、0.031 和 0.013)。BFF 和 BFR 组之间血压变化(∆SBP 和 ∆DBP)相似(P>0.05),而 ∆MAP 则不同(P=0.016)。两组间血糖水平和心率变化无显著差异。虽然 BFR 组的 SmO2 基线较低(P=0.049),但 BFF 和 BFR 组之间的 SmO2min 和 SmO2max 无显著差异。
两组间血糖水平的相似下降表明 BFR 运动有利于降低血糖。在 BFR 运动中观察到的较高血压仍处于安全范围内。这些结果表明,2 型糖尿病患者可以安全地进行 BFR 有氧运动;然而,需要进一步的研究。