Zhuang Shiyang, Li Hongyan, Lin Yiming, Huang Mei, Zhang Wenming, Zhang Xuehui, Lin Yunzhi, Zhang Chaofan
Department of Stomatology, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Stomatology, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; School of Stomatology, Fujian Medical University, Fuzhou, China.
Department of Orthopaedic Surgery, the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Department of Orthopaedic Surgery, National Regional Medical Center, Binhai Campus of the First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Fujian Provincial Institute of Orthopedics, The First Affiliated Hospital, Fujian Medical University, Fuzhou, China; Fujian Orthopedic Bone and Joint Disease and Sports Rehabilitation Clinical Medical Research Center, Fuzhou, China.
Int Dent J. 2025 Apr;75(2):514-523. doi: 10.1016/j.identj.2024.07.007. Epub 2024 Aug 3.
COVID-19 infection shows variant symptoms apart from respiratory symptoms, including the orofacial pain. We aim to research the morbidity, characteristics and potential risk factors of orofacial pain associated with COVID-19 pandemic in China from December 2022 to early 2023.
A cross-sectional survey was conducted in Fujian Province, China. The demographic and characteristic data of the subjects were collected and analysed.
A total of 1526 subjects responded to the survey. The morbidity of orofacial pain increased significantly before and after COVID-19 infection. (42.26% vs. 46.52%, P < .001) A total of 217 (14.22%) subjects with orofacial pain before COVID-19 infection reported the phenomenon of "COVID-19 infection with orofacial pain" (CIOP). Univariate and multivariate logistic regression showed that male (OR = 1.761, P < .001) and other symptoms of COVID-19 (OR = 1.494, P < .001) may be the risk factors for the aggravation of CIOP, while the time of first infection (OR = 0.580, P = .004) and preference for drinking tea or coffee (OR = 0.610, P = .003) may be the protective factors for the aggravation of CIOP. While, the subjects who did not concern about the spread of COVID-19 in oral treatment (OR = 0.639, P = .001), female (OR = 0.749, P = .03), education level (OR = 1.687, P < .001) and income level (OR = 1.796, P < .001), higher PSS-10 score (OR = 1.076, P < .001), and more drugs taken for infection (OR = 1.330, P < .001) were more willing to seek medical treatment.
The morbidity of orofacial pain appears to have increased significantly due to the COVID-19 epidemic; a number of factors can influence the CIOP including gender, infection period, and beverage preference' psychological factors, gender, education and income level can also influence the intent to seek a dentist.
新型冠状病毒肺炎（COVID-19）感染除呼吸道症状外还表现出多种症状，包括口面部疼痛。我们旨在研究2022年12月至2023年初中国与COVID-19大流行相关的口面部疼痛的发病率、特征及潜在危险因素。
在中国福建省进行了一项横断面调查。收集并分析了受试者的人口统计学和特征数据。
共有1526名受试者参与了调查。COVID-19感染前后口面部疼痛的发病率显著增加。（42.26%对46.52%，P <.001）共有217名（14.22%）在COVID-19感染前有口面部疼痛的受试者报告了“口面部疼痛伴COVID-19感染”（CIOP）现象。单因素和多因素逻辑回归显示，男性（OR = 1.761，P <.001）和COVID-19的其他症状（OR = 1.494，P <.001）可能是CIOP加重的危险因素，而首次感染时间（OR = 0.580，P =.004）和对喝茶或咖啡的偏好（OR = 0.610，P =.003）可能是CIOP加重的保护因素。同时，在口腔治疗中不关注COVID-19传播的受试者（OR = 0.639，P =.001）、女性（OR = 0.749，P =.03）、教育水平（OR = 1.687，P <.001）和收入水平（OR = 1.796，P <.001）、较高的PSS-10评分（OR = 1.076，P <.001）以及因感染服用更多药物（OR = 1.330，P <.001）的受试者更愿意寻求医疗治疗。
由于COVID-19疫情，口面部疼痛的发病率似乎显著增加；多种因素可影响CIOP，包括性别、感染时期和饮料偏好，心理因素、性别、教育和收入水平也可影响寻求牙医治疗的意愿。
