Khoswanto Christian, Dewi Ira Kusuma
Department of Oral Biology Faculty of Dentistry, Airlangga University Surabaya, Surabaya, Indonesia.
Dentistry Clinic Research, Surabaya, Indonesia.
J Adv Vet Anim Res. 2024 Jun 6;11(2):291-295. doi: 10.5455/javar.2024.k775. eCollection 2024 Jun.
The study aimed to ascertain how (Ten.) Steenis Gel affects the expression of protein dentin matrix protein-1 (DMP-1) in alveolar Wistar rats after tooth extraction.
Rats were given (Ten.) Steenis gel was in the socket after tooth extraction, and then the wound was sutured. The rats were sacrificed for 8 and 15 days following tooth extraction. The results on the 8 and 15 days demonstrate that the expression of DMP-1 in the treatment group is significantly higher than in the control group.
Expression of DMP-1 in the socket after tooth extraction on days 8 and 15 with a 400x magnification light microscope in both of the (Ten.) Steenis gel treatment groups showed significant differences compared to the control group.
The use of (Ten.) Steenis gel can stimulate DMP-1 expression in alveolar bone after tooth extraction.
本研究旨在确定(十)斯泰尼斯凝胶对拔牙后Wistar大鼠牙槽骨中牙本质基质蛋白-1(DMP-1)表达的影响。
拔牙后在大鼠牙槽窝内给予(十)斯泰尼斯凝胶,然后缝合伤口。拔牙后8天和15天处死大鼠。第8天和第15天的结果表明,治疗组中DMP-1的表达明显高于对照组。
在400倍放大率的光学显微镜下,(十)斯泰尼斯凝胶治疗组在拔牙后第8天和第15天牙槽窝内DMP-1的表达与对照组相比有显著差异。
使用(十)斯泰尼斯凝胶可刺激拔牙后牙槽骨中DMP-1的表达。