Brain-Computer Interface Laboratory, Department of Biomedical Engineering, Faculty of Engineering, Mahidol University, Nakhon Pathom, Thailand.
Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Sci Rep. 2024 Aug 5;14(1):18059. doi: 10.1038/s41598-024-68628-9.
The aim of the present study was to identify cognitive alterations, as indicated by event-related potentials (ERPs), after one month of daily exposure to theta binaural beats (BBs) for 10 minutes. The recruited healthy subjects (n = 60) were equally divided into experimental and control groups. For a month, the experimental group was required to practice BBs listening daily, while the control group did not. ERPs were assessed at three separate visits over a span of one month, with a two-week interval between each visit. At each visit, ERPs were measured before and after listening. The auditory and visual ERPs significantly increased the auditory and visual P300 amplitudes consistently at each visit. BBs enhanced the auditory N200 amplitude consistently across all visits, but the visual N200 amplitude increased only at the second and third visits. Compared to the healthy controls, daily exposure to BBs for two weeks resulted in increased auditory P300 amplitude. Additionally, four weeks of BBs exposure not only increased auditory P300 amplitude but also reduced P300 latency. These preliminary findings suggest that listening to BBs at 6 Hz for 10 minutes daily may enhance certain aspects of cognitive function. However, further research is needed to confirm these effects and to understand the underlying mechanisms. Identifying the optimal duration and practice of listening to 6 Hz BBs could potentially contribute to cognitive enhancement strategies in healthy individuals.
本研究旨在通过事件相关电位（ERPs）来确定认知改变，研究对象为一个月内每天接受 10 分钟θ双声拍（BB）刺激的健康受试者。共招募了 60 名健康受试者，平均分为实验组和对照组。实验组在一个月内每天需要练习 BBs 听法，而对照组不进行练习。在一个月内的三个不同时间点进行了三次 ERPs 评估，每次评估之间间隔两周。每次评估时，在听前和听后都测量了 ERPs。听觉和视觉 ERPs 在每次评估中都显著增加了听觉和视觉 P300 波幅。BBs 在所有评估中都一致地增加了听觉 N200 波幅，但视觉 N200 波幅仅在第二和第三次评估中增加。与健康对照组相比，两周的 BBs 暴露使听觉 P300 波幅增加。此外，四周的 BBs 暴露不仅增加了听觉 P300 波幅，还降低了 P300 潜伏期。这些初步发现表明，每天听 10 分钟 6Hz 的 BBs 可能会增强某些认知功能。然而，还需要进一步的研究来证实这些效果，并了解其潜在机制。确定每天听 6Hz BBs 的最佳持续时间和练习方法，可能有助于制定健康个体的认知增强策略。
