口服阿莫西林，一种治疗神经梅毒的替代疗法。
Oral amoxycillin, an alternative treatment for neurosyphilis.
作者信息
Morrison R E, Harrison S M, Tramont E C
出版信息
Genitourin Med. 1985 Dec;61(6):359-62. doi: 10.1136/sti.61.6.359.
Abstract
A serum amoxycillin concentration of 0.11 g/l was established as being treponemicidal in a rabbit model with orchitis. Seventeen patients treated with amoxycillin 2 g by mouth three times a day plus 500 mg probenecid twice a day attained treponemicidal CSF amoxycillin concentrations. Thus amoxycillin by mouth offers an effective alternative method for treating patients with neurosyphilis.
摘要
在兔睾丸炎模型中，已确定血清阿莫西林浓度为0.11g/L时具有杀梅毒螺旋体作用。17例患者每天口服3次2g阿莫西林加每天2次500mg丙磺舒，其脑脊液中阿莫西林浓度达到了杀梅毒螺旋体水平。因此，口服阿莫西林为治疗神经梅毒患者提供了一种有效的替代方法。
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本文引用的文献
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