CAS Key Laboratory of Theoretical Physics, Institute of Theoretical Physics, Chinese Academy of Sciences , Beijing 100190, People's Republic of China.
School of Physical Sciences, University of Chinese Academy of Sciences, 19A Yuquan Road , Beijing 100049, People's Republic of China.
J R Soc Interface. 2024 Aug;21(217):20240221. doi: 10.1098/rsif.2024.0221. Epub 2024 Aug 7.
Cilia can beat collectively in the form of a metachronal wave, and we investigate how near-field hydrodynamic interactions between cilia can influence the collective response of the beating cilia. Based on the theoretical framework developed in the work of Meng . (Meng . 2021 , e2102828118), we find that the first harmonic mode in the driving force acting on each individual cilium can determine the direction of the metachronal wave after considering the finite size of the beating trajectories, which is confirmed by our agent-based numerical simulations. The stable wave patterns, e.g. the travelling direction, can be controlled by the driving forces acting on the cilia, based on which one can change the flow field generated by the cilia. This work can not only help to understand the role of the hydrodynamic interactions in the collective behaviours of cilia, but can also guide future designs of artificial cilia beating in the desired dynamic mode.
纤毛可以集体以同步波的形式跳动，我们研究纤毛之间的近场水动力相互作用如何影响跳动纤毛的集体反应。基于 Meng 的工作中发展的理论框架。（Meng. 2021 ，e2102828118），我们发现，考虑到跳动轨迹的有限大小，作用于每个单独纤毛的驱动力中的第一谐模可以确定同步波的方向，这得到了我们基于代理的数值模拟的证实。稳定的波型，例如传播方向，可以通过作用于纤毛的驱动力来控制，基于此，可以改变纤毛产生的流场。这项工作不仅有助于理解水动力相互作用在纤毛集体行为中的作用，而且还可以指导未来以期望的动态模式设计人工纤毛跳动。
