Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, Hefei, Anhui, China.
Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Beijing Ophthalmology & Visual Sciences Key Laboratory, Capital Medical University, Beijing, China.
Int J Rheum Dis. 2024 Aug;27(8):e15285. doi: 10.1111/1756-185X.15285.
To investigate the age-standardized prevalence rate (ASPR) and temporal trends for hip, knee, hand, and other osteoarthritis (OA) at a global, continental, and national level.
The estimates and 95% uncertainty intervals (UIs) for case number and ASPR of OA were derived from the Global Burden of Diseases Study (GBD) 2019. The joinpoint regression analysis was utilized to examine the temporal trends from 1990 to 2019.
In 2019, the global ASPR of hip, knee, hand, and other OA was 400.95 (95% UI: 312.77-499.41), 4375.95 (95% UI: 3793.04-5004.9), 1726.38 (95% UI: 1319.91-2254.85), and 745.62 (95% UI: 570.16-939.8). As for the ASPR of hip OA, hand OA, and other OA, Europe and America had higher rates than Asia and Africa, and Asia was second only to America in knee OA ASPRs. The period 1990-2019, the ASPR at global level dropped significantly for hand OA (AAPC = -0.4%, 95% CI: -0.47 to -0.34) and increased significantly for hip OA (AAPC = 0.43%, 95% CI: 0.39-0.46), knee OA (AAPC = 0.17%, 95% CI: 0.09-0.24) and other OA (AAPC = 0.16%, 95% CI: 0.15-0.17). Different continents, countries, and periods demonstrated significant changes.
Globally, America has the highest OA burden and Asia has a higher knee OA burden. Appropriate prevention and control measures to reduce modifiable risk factors are needed to reduce the burden of OA.
在全球、大陆和国家层面上，研究髋、膝、手和其他部位骨关节炎（OA）的年龄标准化患病率（ASPR）和时间趋势。
OA 的病例数和 ASPR 的估计值及其 95%置信区间（UI）来自 2019 年全球疾病负担研究（GBD）。使用 Joinpoint 回归分析研究了 1990 年至 2019 年的时间趋势。
2019 年，全球髋、膝、手和其他部位 OA 的 ASPR 分别为 400.95（95% UI：312.77-499.41）、4375.95（95% UI：3793.04-5004.9）、1726.38（95% UI：1319.91-2254.85）和 745.62（95% UI：570.16-939.8）。在髋 OA、手 OA 和其他 OA 的 ASPR 方面，欧美地区的比率高于亚洲和非洲，而亚洲地区的膝 OA ASPR 仅次于美国。1990-2019 年期间，全球手 OA 的 ASPR 显著下降（AAPC=-0.4%，95%CI：-0.47 至-0.34），髋 OA（AAPC=0.43%，95%CI：0.39-0.46）、膝 OA（AAPC=0.17%，95%CI：0.09-0.24）和其他 OA（AAPC=0.16%，95%CI：0.15-0.17）的 ASPR 显著增加。不同的大陆、国家和时期均发生了显著变化。
全球范围内，美洲地区的 OA 负担最重，而亚洲地区的膝 OA 负担最重。需要采取适当的预防和控制措施来减少可改变的危险因素，以降低 OA 的负担。
