Mišković Vanja, Greco Immacolata, Minetti Christophe, Cialdai Francesca, Monici Monica, Gazzi Arianna, Marcellino Jeremiah, Samad Yarjan Abdul, Delogu Lucia Gemma, Ferrari Andrea C, Iorio Carlo Saverio
Centre for Research and Engineering in Space Technologies, École Polytechnique de Bruxelles, Université libre de Bruxelles, Brussels, Belgium.
ASAcampus Joint Laboratory, ASA Research Division, Department of Experimental and Clinical Biomedical Sciences « Mario Serio », University of Florence, Florence, Italy.
NPJ Microgravity. 2024 Aug 8;10(1):83. doi: 10.1038/s41526-024-00388-2.
Exposure to altered gravity influences cellular behaviour in cell cultures. Hydrogels are amongst the most common materials used to produce tissue-engineering scaffolds, and their mechanical properties play a crucial role in cell-matrix interaction. However, little is known about the influence of altered gravity on hydrogel properties. Here we study the mechanical properties of Poly (ethylene glycol) diacrylate (PEGDA) and PEGDA incorporated with graphene oxide (GO) by performing tensile tests in micro and hypergravity during a Parabolic flight campaign, and by comparing them to the same tests performed in Earth gravity. We show that gravity levels do not result in a statistically significant difference in Young's modulus.
暴露于改变的重力环境会影响细胞培养中的细胞行为。水凝胶是用于制造组织工程支架的最常见材料之一，其机械性能在细胞与基质的相互作用中起着至关重要的作用。然而，关于改变的重力对水凝胶性能的影响却知之甚少。在这里，我们通过在抛物线飞行任务期间在微重力和超重力环境下进行拉伸试验，并将其与在地球重力环境下进行的相同试验进行比较，研究了聚（乙二醇）二丙烯酸酯（PEGDA）和掺有氧化石墨烯（GO）的PEGDA的机械性能。我们发现重力水平不会导致杨氏模量出现统计学上的显著差异。
