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Elimination of plasmids by new 4-quinolones.

作者信息

Weisser J, Wiedemann B

出版信息

Antimicrob Agents Chemother. 1985 Nov;28(5):700-2. doi: 10.1128/AAC.28.5.700.

Abstract

Nalidixic acid and six of the new 4-quinolones eliminated F'lac and various native R plasmids from Escherichia coli at one half or one quarter the MIC. Four of eight plasmids tested were cured by all derivatives, with frequencies from 10 to 98%. Quinolones did not eliminate all plasmids that were cured by novobiocin, and vice versa.

摘要

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