Kyriazidis Ioannis, Demiri Efterpi, Foroglou Pericles
Department of Plastic and Reconstructive Surgery, General Hospital Papageorgiou, Thessaloniki, GRC.
Department of Plastic and Reconstructive Surgery, School of Medicine, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Cureus. 2024 Jul 9;16(7):e64163. doi: 10.7759/cureus.64163. eCollection 2024 Jul.
Keloids are complex fibroproliferative disorders with diverse clinical presentations. Spontaneous keloids (SKs) represent a rare subtype that emerges without any known preceding traumatic event. This report presents a case of familial spontaneous keloids appearing on the thoracic region in two brothers with no prior history of trauma or keloid occurrence in other family members. The lesions exhibited progressive growth over several years but responded to cycles of triamcinolone treatment. This case underscores an unusual spontaneous occurrence of keloids in the thoracic region of two siblings, highlighting the potential genetic predisposition in the aetiology of these lesions. Additionally, this instance reinforces the concept that keloids can develop spontaneously without any apparent trauma in the affected area.
瘢痕疙瘩是具有多种临床表现的复杂纤维增生性疾病。自发性瘢痕疙瘩（SKs）是一种罕见的亚型，在没有任何已知先前创伤事件的情况下出现。本报告介绍了一例家族性自发性瘢痕疙瘩病例，该病例出现在两兄弟的胸部区域，其他家庭成员既往无创伤或瘢痕疙瘩发生史。这些病变在几年内呈渐进性生长，但对曲安奈德治疗周期有反应。该病例强调了在两名兄弟姐妹的胸部区域出现不寻常的自发性瘢痕疙瘩，突出了这些病变病因中潜在的遗传易感性。此外，这个病例强化了瘢痕疙瘩可以在受影响区域没有任何明显创伤的情况下自发形成的概念。
