Department of Digestive Endoscopy, Yueqing People's Hospital Affiliated to Wenzhou Medical University, 325600 Yueqing, Zhejiang, China.
Department of Gastroenterology, Wenzhou Hospital of Integrated Traditional Chinese and Western Medicine, 325000 Wenzhou, Zhejiang, China.
Actas Esp Psiquiatr. 2024 Aug;52(4):495-502. doi: 10.62641/aep.v52i4.1798.
The relevant survey has shown a high incidence of psychiatric complications in patients with pancreatic cancer. While some studies have explored the factors influencing psychological complications in pancreatic cancer patients, some factors validated in other populations have not been confirmed in the pancreatic cancer population. This study aims to explore the predictors of psychiatric complications in patients with pancreatic cancer.
Patients with pancreatic cancer admitted to Yueqing People's Hospital Affiliated to Wenzhou Medical University, from January 2021 to January 2022 were retrospectively analyzed. The structured clinical interview (SCID-I) based on Diagnostic and Statistical Manual of Mental Disorders (DSM-IV) was used by nurses to assess the incidence of psychiatric complications during hospitalization (baseline) and 3 months after the start of treatment. Binary logistic regression was used to identify predictors of psychiatric complications.
80 patients were enrolled in this study and 8 patients were diagnosed with psychiatric complications at base line. Among the rest 72 patients, 8 patients (11.11%) had new-onset psychiatric complications at 3-month follow-up. Gender (Odds Ratio (OR) = 1.674, p = 0.019), monthly income (OR = 1.735, p = 0.023) and sadness (M.D. Anderson Symptom Inventory (MDASI)) (OR = 1.804, p = 0.001) were all predictors for psychiatric complications in patients with pancreatic cancer.
Gender, monthly income and MDASI score are predictors of psychiatric complications in patients with pancreatic cancer.
相关调查显示，胰腺癌患者的精神并发症发生率较高。虽然一些研究探讨了影响胰腺癌患者心理并发症的因素，但一些在其他人群中验证的因素在胰腺癌人群中尚未得到证实。本研究旨在探讨胰腺癌患者精神并发症的预测因素。
回顾性分析 2021 年 1 月至 2022 年 1 月期间温州医科大学附属乐清人民医院收治的胰腺癌患者。护士采用基于《精神障碍诊断与统计手册》（DSM-IV）的结构化临床访谈（SCID-I）评估住院期间（基线）和治疗开始后 3 个月的精神并发症发生率。采用二元逻辑回归识别精神并发症的预测因素。
本研究共纳入 80 例患者，基线时有 8 例患者被诊断为精神并发症。在其余 72 例患者中，有 8 例（11.11%）在 3 个月随访时出现新发精神并发症。性别（比值比（OR）=1.674，p=0.019）、月收入（OR=1.735，p=0.023）和悲伤（MD 安德森症状评估量表（MDASI））（OR=1.804，p=0.001）均是胰腺癌患者精神并发症的预测因素。
性别、月收入和 MDASI 评分是胰腺癌患者精神并发症的预测因素。
