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Next-Generation Probiotics as Novel Therapeutics for Improving Human Health: Current Trends and Future Perspectives.下一代益生菌作为改善人类健康的新型疗法:当前趋势与未来展望
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Front Microbiol. 2024 Jan 11;14:1241259. doi: 10.3389/fmicb.2023.1241259. eCollection 2023.
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Bacillus Subtilis (BG01-4) Improves Self-Reported Symptoms for Constipation, Indigestion, and Dyspepsia: A Phase 1/2A Randomized Controlled Trial.枯草芽孢杆菌(BG01-4)改善便秘、消化不良和胃食管反流病的自报告症状:一项 1/2A 期随机对照试验。
Nutrients. 2023 Oct 24;15(21):4490. doi: 10.3390/nu15214490.
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The effect of probiotic supplementation on the clinical and para-clinical findings of multiple sclerosis: a randomized clinical trial.益生菌补充对多发性硬化症的临床和辅助临床发现的影响:一项随机临床试验。
Sci Rep. 2023 Oct 30;13(1):18577. doi: 10.1038/s41598-023-46047-6.
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Paraprobiotics: definition, manufacturing methods, and functionality.副益生菌:定义、生产方法及功能
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Protective effects of a new generation of probiotic Bacteroides fragilis against colitis in vivo and in vitro.新一代益生菌脆弱拟杆菌对体内和体外结肠炎的保护作用。
Sci Rep. 2023 Sep 22;13(1):15842. doi: 10.1038/s41598-023-42481-8.
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The curious case of .令人好奇的案例。
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A Keystone Gut Bacterium -A Potential Biotherapeutic Agent for Obesity and Associated Metabolic Diseases.一种关键肠道细菌——肥胖及相关代谢性疾病的潜在生物治疗剂。
Foods. 2023 Jun 26;12(13):2485. doi: 10.3390/foods12132485.
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The Role of Next-Generation Probiotics in Obesity and Obesity-Associated Disorders: Current Knowledge and Future Perspectives.下一代益生菌在肥胖和肥胖相关疾病中的作用:当前的知识和未来的观点。
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Bioinformatics and its role in the study of the evolution and probiotic potential of lactic acid bacteria.生物信息学及其在乳酸菌进化与益生菌潜力研究中的作用。
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从肠道或各种环境中分离出的非乳酸菌益生菌。

Non-lactic acid bacteria probiotics isolated from intestine or various circumstances.

作者信息

Lee Na-Kyoung, Jang Hye Ji, Paik Hyun-Dong

机构信息

Department of Food Science and Biotechnology of Animal Resource, Konkuk University, Seoul, 05029 Republic of Korea.

出版信息

Food Sci Biotechnol. 2024 Jun 14;33(9):1997-2007. doi: 10.1007/s10068-024-01608-x. eCollection 2024 Jul.

DOI:10.1007/s10068-024-01608-x
PMID:39130655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11315843/
Abstract

Probiotics are live microorganisms beneficial to host health, predominantly comprising lactic acid bacteria (LAB) such as . Additional non-LAB probiotics, termed intestinal isolates, encompass next-generation strains like , , , , etc. and alongside externally sourced , , , and . Intestinal-derived probiotics represent strictly anaerobic strains with challenging culturing requirements, contrasting with the aerobic nature of probiotics and the ease of culturing . These strains exhibit diverse health-promoting properties, encompassing antimicrobial, anticancer, antioxidant, and vitamin production capabilities, albeit contingent upon strain specificity. This review delineates the characteristics, culturing conditions, and health advantages associated with non-LAB probiotics.

摘要

益生菌是对宿主健康有益的活微生物,主要包括乳酸菌等。其他非乳酸菌益生菌,称为肠道分离株,包括下一代菌株,如等等,以及外源的、、和。肠道来源的益生菌代表严格厌氧的菌株,培养要求具有挑战性,这与益生菌的需氧性质和易于培养形成对比。这些菌株表现出多种促进健康的特性,包括抗菌、抗癌、抗氧化和维生素生产能力,尽管这些特性取决于菌株特异性。本综述阐述了非乳酸菌益生菌的特征、培养条件和健康益处。