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获得机械循环支持方面的种族、族裔、社会经济和地理不平等。

Racial, Ethnic, Socioeconomic, and Geographic Inequities in Access to Mechanical Circulatory Support.

作者信息

Nathan Ashwin S, Reddy Kriyana P, Eberly Lauren A, Fanaroff Alexander, Julien Howard M, Fiorilli Paul, Wald Joyce, Mutaawe Shafik, Cevasco Marisa, Bermudez Christian, Kapur Navin K, Basir Mir Babir, Roswell Robert, Groeneveld Peter W, Giri Jay

机构信息

Penn Cardiovascular Outcomes, Quality, and Evaluative Research Center, University of Pennsylvania, Philadelphia, Pennsylvania.

Division of Cardiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

J Soc Cardiovasc Angiogr Interv. 2023 Oct 25;3(1):101193. doi: 10.1016/j.jscai.2023.101193. eCollection 2024 Jan.

Abstract

BACKGROUND

Hospital admissions for cardiogenic shock have increased in the United States. Temporary mechanical circulatory support (tMCS) can be used to acutely stabilize patients. We sought to evaluate the presence of racial, ethnic, and socioeconomic inequities in access to MCS in the United States among patients with cardiogenic shock.

METHODS

Medicare data were used to identify patients with cardiogenic shock admitted to hospitals with advanced tMCS (microaxial left ventricular assist device [mLVAD] or extracorporeal membranous oxygenation [ECMO]) capabilities within the 25 largest core-based statistical areas, all major metropolitan areas. We modeled the association between patient race, ethnicity, and socioeconomic status and use of mLVAD or ECMO.

RESULTS

After adjusting for age and clinical comorbidities, dual eligibility for Medicaid was associated with a 19.9% (95% CI, 11.5%-27.4%) decrease in odds of receiving mLVAD in a patient with cardiogenic shock ( < .001). After adjusting for age, clinical comorbidities, and dual eligibility for Medicaid, Black race was associated with 36.7% (95% CI, 28.4%-44.2%) lower odds of receiving mLVAD in a patient with cardiogenic shock. Dual eligibility for Medicaid was associated with a 62.0% (95% CI, 60.8%-63.1%) decrease in odds of receiving ECMO in a patient with cardiogenic shock ( < .001). Black race was associated with 36.0% (95% CI, 16.6%-50.9%) lower odds of receiving ECMO in a patient with cardiogenic shock, after adjusting for Medicaid eligibility.

CONCLUSIONS

We identified large and significant racial, ethnic, and socioeconomic inequities in access to mLVAD and ECMO among patients presenting with cardiogenic shock to metropolitan hospitals with active advanced tMCS programs. These findings highlight systematic inequities in access to potentially lifesaving therapies.

摘要

背景

在美国,因心源性休克住院的人数有所增加。临时机械循环支持(tMCS)可用于使患者迅速稳定病情。我们试图评估美国心源性休克患者在获得机械循环支持方面是否存在种族、民族和社会经济不平等现象。

方法

利用医疗保险数据,在25个最大的基于核心的统计区域(所有主要大都市地区)内,确定入住具备先进tMCS(微型轴流左心室辅助装置[mLVAD]或体外膜肺氧合[ECMO])能力医院的心源性休克患者。我们对患者的种族、民族和社会经济地位与mLVAD或ECMO的使用之间的关联进行了建模。

结果

在调整年龄和临床合并症后,符合医疗补助双重资格与心源性休克患者接受mLVAD的几率降低19.9%(95%CI,11.5%-27.4%)相关(P<0.001)。在调整年龄、临床合并症和医疗补助双重资格后,黑人种族与心源性休克患者接受mLVAD的几率降低36.7%(95%CI,28.4%-44.2%)相关。符合医疗补助双重资格与心源性休克患者接受ECMO的几率降低62.0%(95%CI,60.8%-63.1%)相关(P<0.001)。在调整医疗补助资格后,黑人种族与心源性休克患者接受ECMO的几率降低36.0%(95%CI,16.6%-50.9%)相关。

结论

我们发现,在设有活跃的先进tMCS项目的大都市医院中,心源性休克患者在获得mLVAD和ECMO方面存在巨大且显著的种族、民族和社会经济不平等现象。这些发现凸显了在获得可能挽救生命的治疗方面存在的系统性不平等。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8c73/11307759/fa8a4a615533/ga1.jpg

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