Jiang Yizi, Jia Min
First Clinical Medical College, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People's Republic of China.
Department of Dermatology, The First Affiliated Hospital of Guizhou University of Traditional Chinese Medicine, Guizhou University of Traditional Chinese Medicine, Guiyang, Guizhou, People's Republic of China.
Clin Cosmet Investig Dermatol. 2024 Aug 5;17:1763-1772. doi: 10.2147/CCID.S471528. eCollection 2024.
The weight-adjusted-waist index (WWI) is a new indicator that may be used to assess obesity. However, there has never been any prior research indicating a link between psoriasis and WWI. Hence, the aim of this investigation is to search for the correlation between the two.
Cross-sectional analyses used National Health and Nutrition Examination Survey (NHANES) data from 2003 to 2006 and 2019 to 2014. Through multivariate logistic regression, the connection between Psoriasis and WWI was explored, while subgroup analyses aimed to identify possible causes. Furthermore, Smoothed curve fitting was also performed to further understand the association. The non-linear connection was examined through the use of threshold effects.
There were 21,916 participants over the age of 20 in the research. Psoriasis and WWI were revealed to be positively correlated [1.25 (1.14, 1.38)] using multivariate logistic regression analysis. This association was observed in both men [1.50(1.29,1.78)] and hypertensive patients [1.37(1.16,1.62)] in subgroup analysis. Furthermore, we noticed a curvilinear association between WWI and psoriasis, wherein the inflection point was identified as 10.15. To the left of the inflection point, there existed a negative correlation [0.12(0.02,0.91)] while to the right, a positive one [1.68(1.03,2.72)].
According to our findings, psoriasis and WWI are related, although more extensive prospective research is still required to support this conclusion.
体重调整腰围指数（WWI）是一种可用于评估肥胖的新指标。然而，此前从未有研究表明银屑病与WWI之间存在关联。因此，本研究的目的是探寻两者之间的相关性。
横断面分析使用了2003年至2006年以及2019年至2014年的美国国家健康与营养检查调查（NHANES）数据。通过多变量逻辑回归，探讨银屑病与WWI之间的联系，同时进行亚组分析以确定可能的原因。此外，还进行了平滑曲线拟合以进一步了解这种关联。通过阈值效应检验非线性关系。
该研究中有21916名年龄超过20岁的参与者。多变量逻辑回归分析显示，银屑病与WWI呈正相关[1.25（1.14，1.38）]。在亚组分析中，男性[1.50（1.29，1.78）]和高血压患者[1.37（1.16，1.62）]中均观察到这种关联。此外，我们注意到WWI与银屑病之间存在曲线关联，其中拐点确定为10.15。在拐点左侧，存在负相关[0.12（0.02，0.91）]，而在右侧，则为正相关[1.68（1.03，2.72）]。
根据我们的研究结果，银屑病与WWI相关，尽管仍需要更广泛的前瞻性研究来支持这一结论。
