Department of Dermatology, Venereology and Allergology, Medical University of Gdansk, 80-214 Gdansk, Poland.
Medicina (Kaunas). 2023 Nov 15;59(11):2006. doi: 10.3390/medicina59112006.
: Psoriasis is a common, chronic, and immune-mediated inflammatory skin disease recognized to lead to a wide range of comorbid disorders, mainly obesity. The study aimed to evaluate the problem of overweightness and obesity among psoriasis patients in the context of their prevalence and influence on the disease course. : The study group encompassed 147 adult patients with plaque psoriasis. : The prevalences of overweightness (39.46%) and obesity (37.41%) demonstrated in the study showed the strong predisposition of psoriatic patients for abnormal body mass. The vast majority (77%) of subjects with psoriatic arthritis were overweight or obese. The results of the correlation analysis revealed the significant impacts of overweightness and obesity, as defined by the BMI index, on modifying the severity of psoriasis (as assessed by the PASI with a correlation coefficient of R = 0.23, = 0.016; and BSA values with a correlation coefficient of R = 0.21, = 0.023), particularly in contrast to patients with a normal body mass. : Overweightness and obesity constitute a major health burden among psoriatic patients, influencing the disease course and severity. Enhanced understanding of the phenomenon may directly translate into improving disease management and overall patient care.
银屑病是一种常见的、慢性的、免疫介导的炎症性皮肤病,已知会导致多种合并症,主要是肥胖症。本研究旨在评估银屑病患者超重和肥胖的问题,以及它们对疾病过程的影响。
研究组包括 147 名成年斑块状银屑病患者。
研究中显示的超重(39.46%)和肥胖(37.41%)患病率表明,银屑病患者有异常体重的强烈倾向。绝大多数(77%)的银屑病关节炎患者超重或肥胖。相关性分析的结果表明,BMI 指数定义的超重和肥胖对改变银屑病的严重程度有显著影响(PASI 评分的相关系数为 R = 0.23,p = 0.016;BSA 值的相关系数为 R = 0.21,p = 0.023),特别是与体重正常的患者相比。
超重和肥胖是银屑病患者的主要健康负担,影响疾病过程和严重程度。增强对这一现象的理解可能直接转化为改善疾病管理和整体患者护理。
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