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中国女性皮肤衰老的特征及遗传模式:一项母女代际研究

The Characteristics and Inheriting Pattern of Skin Aging in Chinese Women: An Intergenerational Study of Mothers and Daughters.

作者信息

Zhang Zhuying, Shi Mai, Li Jinghui, Chen Dian, Ren Jie, Li Zhenghui, Tuan Hsiaohan, Zhao Yi

机构信息

Department of Dermatology, Beijing Tsinghua Changgung Hospital, Beijing, People's Republic of China.

Photomedicine Laboratory, Institute of Precision Medicine, Tsinghua University, Beijing, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2024 Aug 5;17:1773-1782. doi: 10.2147/CCID.S468477. eCollection 2024.

DOI:10.2147/CCID.S468477
PMID:39132029
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11315646/
Abstract

INTRODUCTION

The aging of the skin, which is affected by both external and internal causes, can reflect the external age and the internal health status. While the aging characteristics differ across ethnic groups, the specific changes in skin aging within the Chinese population have been underexplored. Moreover, investigating the similarity of aging skin characteristics between parent-offspring pairs remains uncharted territory. This study aims to fill these gaps by examining the skin aging features of Chinese women and assessing the similarity in aging skin characteristics between mother-daughter pairs.

METHODS

A total of 40 mother-daughter pairs were recruited and analyzed. The perceived ages of the participants were evaluated, and their aging skin traits were systematically graded. Statistical methods were employed to discern the trends of the aging skin characteristics. By introducing a novel similarity parameter, we compared whether various skin aging characteristics have similar patterns between mothers and daughters.

RESULTS

Our findings indicate that age 50 represents a pivotal point in skin aging. Beyond this age, the increase in rhytides and laxity scores accelerated noticeably, whereas the escalation in dyschromia scores became less marked. By introducing similar parameters between mother-daughter pairs and the radar map, we discovered that the skin aging characteristics are remarkably consistent between mother-daughter pairs.

CONCLUSION

Understanding the main aging skin characteristics of different age groups can allow caregivers to devise treatments for preventing skin aging in women of various ages. The mother's skin aging trend is also significant for the daughter's skin aging prevention.

摘要

引言

皮肤老化受内外因素影响,能反映外在年龄和内在健康状况。虽然不同种族的老化特征有所不同,但中国人群皮肤老化的具体变化尚未得到充分研究。此外,探究亲子对之间老化皮肤特征的相似性仍是未知领域。本研究旨在通过检查中国女性的皮肤老化特征并评估母女对之间老化皮肤特征的相似性来填补这些空白。

方法

共招募并分析了40对母女。评估参与者的感知年龄,并对其老化皮肤特征进行系统分级。采用统计方法来辨别老化皮肤特征的趋势。通过引入一个新的相似性参数,我们比较了母亲和女儿之间各种皮肤老化特征是否具有相似模式。

结果

我们的研究结果表明,50岁是皮肤老化的一个关键点。超过这个年龄,皱纹和松弛评分的增加明显加速,而色素沉着异常评分的上升则变得不那么明显。通过在母女对之间引入相似参数和雷达图,我们发现母女对之间的皮肤老化特征非常一致。

结论

了解不同年龄组的主要老化皮肤特征可以让护理人员为不同年龄段的女性设计预防皮肤老化的治疗方法。母亲的皮肤老化趋势对女儿预防皮肤老化也具有重要意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/9ee10442fe48/CCID-17-1773-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/3b88d4000c50/CCID-17-1773-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/9a32e9bcbb85/CCID-17-1773-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/9ee10442fe48/CCID-17-1773-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/3b88d4000c50/CCID-17-1773-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/9a32e9bcbb85/CCID-17-1773-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa88/11315646/9ee10442fe48/CCID-17-1773-g0003.jpg

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