Department of Biological Sciences, National University of Medical Sciences (NUMS), Rawalpindi, Pakistan.
University Centre Leeds, Leeds, LS3 1AA, UK.
Cancer Treat Res. 2024;191:119-144. doi: 10.1007/978-3-031-55622-7_5.
The effect of nutrition in the development and prognosis of cancer has received a lot of attention. Research shows taking vitamins, which are powerful antioxidants, can significantly lower the risk of cancers. Nutritional supplements suited to a patient's background, genetics, diet, tumour histology, and therapy may be beneficial in some cases. A poor diet may have a negative impact on immunity and treatment tolerance, decreasing the efficacy of chemotherapy in destroying malignant cells. Most cancer patients now take vitamins to supplement regular treatment and/or to decrease side effects from the medicine as well as the underlying ailment. This is a new development in recent decades, whereas taking nutritional supplements while receiving cancer treatment may increase the success of chemotherapy. To enhance the quality of life, lengthen the survival rate, and sustain immunotherapy compliance, additional study into the use of micronutrients in medical treatment is required for cancer patients. The main purpose of this book chapter was to highlight the role of vitamins in cancer and to establish a solid foundation for future research on this exciting topic. The possible impact of some vitamins in various malignancies such as colorectal, breast, prostate, lung, pancreatic, and stomach cancers are investigated.
营养在癌症的发展和预后中的作用受到了广泛关注。研究表明,服用维生素等强效抗氧化剂可以显著降低癌症风险。在某些情况下,适合患者背景、遗传、饮食、肿瘤组织学和治疗的营养补充剂可能是有益的。不良的饮食可能会对免疫力和治疗耐受性产生负面影响,降低化疗药物破坏恶性细胞的效果。现在,大多数癌症患者服用维生素来补充常规治疗和/或减少药物以及潜在疾病的副作用。这是近几十年来的一个新发展,因为在接受癌症治疗时服用营养补充剂可能会提高化疗的成功率。为了提高生活质量、延长生存率并维持免疫疗法的依从性,癌症患者需要进一步研究微量元素在医疗中的应用。本章的主要目的是强调维生素在癌症中的作用,并为这一令人兴奋的课题的未来研究奠定坚实的基础。探讨了一些维生素在结直肠癌、乳腺癌、前列腺癌、肺癌、胰腺癌和胃癌等多种恶性肿瘤中的可能影响。